Double-blind comparison of buspirone and clorazepate in anxious outpatients.

Author: BowdenC L, CohnJ B, FisherJ G, RodosJ J

Paper Details 
Original Abstract of the Article :
Buspirone, a new nonbenzodiazepine anxiolytic agent, was compared with clorazepate in a double-blind, multicenter trial conducted with 336 outpatients who had moderate to severe anxiety. The two treatments were equally effective for relief of symptoms, including anxiety with associated depression. A...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9343(86)90326-8

データ提供:米国国立医学図書館(NLM)

Buspirone vs. Clorazepate: Anxiolytic Showdown

Anxiety is like a desert storm, swirling with feelings of unease and worry. This study delves into the world of anxiolytics, medications designed to calm the mind and reduce anxiety. The research compares the effectiveness of two medications, buspirone and clorazepate, in treating anxious outpatients. The study aims to determine which medication provides more effective relief from anxiety symptoms while also assessing their safety and side effects.

Two Approaches to Calming the Storm

The study found that both buspirone and clorazepate effectively reduced anxiety symptoms, offering relief from the swirling desert storm of worry. However, the study also found that the two medications had different side effect profiles. Clorazepate was associated with more drowsiness and depression, while buspirone was more likely to cause nausea and headache. These findings provide valuable information for clinicians when choosing an appropriate anxiolytic medication for their patients.

Choosing the Right Anxiolytic

The study's findings highlight the importance of considering the potential side effects of anxiolytic medications. Buspirone, while effective in reducing anxiety, may cause nausea and headaches. Clorazepate, on the other hand, can lead to drowsiness and depression. It's important to discuss your individual needs and preferences with your doctor to choose the medication that is most likely to provide the desired benefits while minimizing the risks of side effects.

Dr.Camel's Conclusion

This research, like a wise camel, provides valuable insights into the desert of anxiety. It compares two different approaches to calming the storm of worry, buspirone and clorazepate. The study underscores the importance of considering individual needs and preferences when choosing an anxiolytic medication. Remember, the goal is to find an oasis of peace in the desert of anxiety.

Date :
  1. Date Completed 1986-04-25
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

2870640

DOI: Digital Object Identifier

10.1016/0002-9343(86)90326-8

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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