Radio receptor assay of serum neuroleptic levels in psychiatric patients.

Author: KrskaJ, SampathG, ShahA, SoniS D

Paper Details 
Original Abstract of the Article :
The radioreceptor assay for the measurement of neuroleptic drugs in serum has been used to study the relationship between dose and serum level in schizophrenic patients receiving these drugs. The assay was found to be reproducible and capable of detecting neuroleptics in the sera of patients receivi...See full text at original site
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引用元:
https://doi.org/10.1192/bjp.148.2.187

データ提供:米国国立医学図書館(NLM)

Measuring Neuroleptic Levels in Psychiatric Patients

This study explores the use of a radioreceptor assay to measure serum neuroleptic levels in psychiatric patients. Researchers investigated the relationship between drug dose, serum levels, and extrapyramidal side effects (EPS) in patients receiving various neuroleptic medications. The study found a strong correlation between daily dose and serum levels for each drug, suggesting that the assay could be useful in clinical practice for assessing compliance, monitoring drug levels, and potentially predicting the occurrence of EPS.

Radioreceptor Assay: A Tool for Monitoring Neuroleptic Treatment

The study demonstrates the reliability of the radioreceptor assay in measuring serum neuroleptic levels. The assay showed strong correlation between dose and serum level, providing a reliable method for monitoring drug exposure and potentially adjusting treatment regimens. The study also found that EPS were related to serum neuroleptic levels within individual patients, suggesting a potential for using the assay to predict and manage EPS.

Precision in Psychiatric Treatment: A Step Towards Tailored Care

This research highlights the importance of precision in psychiatric treatment. The radioreceptor assay offers a valuable tool for monitoring drug levels, potentially improving the management of neuroleptic medications and reducing the occurrence of side effects. This research underscores the need for individualized treatment approaches and the importance of monitoring drug levels to optimize treatment outcomes.

Dr.Camel's Conclusion

This research is like a desert explorer’s compass, providing a tool for navigating the complex landscape of psychiatric treatment. The radioreceptor assay offers a valuable method for monitoring drug levels and potentially guiding treatment decisions, leading to more effective and safer care for psychiatric patients.

Date :
  1. Date Completed 1986-06-02
  2. Date Revised 2019-07-05
Further Info :

Pubmed ID

2870755

DOI: Digital Object Identifier

10.1192/bjp.148.2.187

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Languages

English

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