Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study.

Author: AldenkampAlbert P, BackesWalter H, HofmanPaul A M, IJffDominique M, JansenJacobus F A, LazeronRichard H C, de LouwAnton J A, van VeenendaalTamar M

Paper Details 
Original Abstract of the Article :
AIM: To increase our insight in the neuronal mechanisms underlying cognitive side-effects of antiepileptic drug (AED) treatment. METHODS: The relation between functional magnetic resonance-acquired brain network measures, AED use, and cognitive function was investigated. Three groups of patients wi...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491656/

データ提供:米国国立医学図書館(NLM)

Chronic Antiepileptic Drug Use and Brain Network Efficiency

This study explores the complex relationship between chronic antiepileptic drug (AED) use and brain network efficiency. It's like unraveling the intricate connections of a desert ecosystem, examining how medications can impact the delicate balance of brain activity. The researchers used functional magnetic resonance imaging (fMRI) to investigate the effects of AEDs on brain networks in patients with epilepsy. Their findings suggest that chronic AED use might be associated with subtle alterations in brain network organization, particularly in those with more severe cognitive side effects.

AED Use and Brain Network Organization

This study provides a deeper understanding of the potential impact of AEDs on brain networks. It's like discovering a hidden oasis in the desert of neurology, where the complex interplay of brain activity and medication use is revealed. The study suggests that while AEDs can effectively manage epilepsy, they might also influence brain network organization, highlighting the need for continued research to optimize treatment strategies and minimize potential cognitive side effects.

Understanding the Effects of AEDs on the Brain

This study underscores the importance of understanding the potential effects of medications on the brain. It's like learning to navigate a desert landscape, recognizing the subtle changes in the terrain that can impact our journey. Further research is needed to clarify the relationship between AED use, brain network organization, and cognitive function, ensuring that the best possible care is provided to individuals with epilepsy. The quest for better epilepsy treatments continues, and this study provides a valuable insight into the complex interplay of medication, brain networks, and cognitive health.

Dr. Camel's Conclusion

This study offers a glimpse into the complex interplay between AEDs and brain networks. It's like exploring a hidden oasis in the desert of neurology, where the intricate connections of brain activity are revealed. While AEDs offer invaluable relief from seizures, the study highlights the importance of understanding their potential impact on brain function. The journey towards better epilepsy treatments continues, and this research provides a valuable contribution to our understanding of the relationship between medication, brain networks, and cognitive health.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

28717415

DOI: Digital Object Identifier

PMC5491656

Related Literature

SNS
PICO Info
in preparation
Languages

English

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