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Tricyclic and Tetracyclic Antidepressants for the Prevention of Frequent Episodic or Chronic Tension-Type Headache in Adults: A Systematic Review and Meta-Analysis.

Author: BernsteinRebecca, JacksonJeffrey L, KayCynthia, MancusoJosephine M, NickoloffSarah

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Tricyclic antidepressants (TCAs) are modestly effective in reducing chronic tension-type headache and are superior to buspirone. Tetracyclics appear to be ineffective in the prophylactic treatment of chronic tension-type headache.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Tension-type headaches are a common source of pain and suffering. Our purpose was to assess the efficacy of tricyclic (TCA) and tetracyclic antidepressants in the prophylactic treatment of tension-type headache. METHODS: We searched the Cochrane Central Register of Controlled Trials, ME...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698213/

データ提供：米国国立医学図書館（NLM）

Tension-Type Headaches: Finding Relief in the Desert of Pain

Tension-type headaches are a common ailment, causing discomfort and disruption to daily life. This study examines the efficacy of tricyclic (TCA) and tetracyclic antidepressants in the prophylactic treatment of tension-type headaches in adults. Imagine this as a journey through a desert of pain, seeking a remedy to alleviate the discomfort.

Antidepressants' Impact on Headaches

The study found that TCAs were more effective than placebo in reducing headache frequency and the number of analgesic medications consumed. This is like discovering a hidden spring in the desert, offering a source of relief and respite. However, tetracyclics were not found to be effective in the treatment of chronic tension-type headaches. This highlights the need for continued research and development of new treatment strategies to effectively manage tension-type headaches.

Managing Tension-Type Headaches

Tension-type headaches can be frustrating, but there are steps you can take to manage them. Maintaining a healthy lifestyle, including regular exercise, stress management techniques, and a balanced diet, can help prevent and alleviate headaches. It's also important to identify and avoid triggers, such as caffeine, alcohol, and certain foods. Remember, just like a camel needs to avoid harsh sun and dehydration, we need to be mindful of our health and take steps to prevent and manage our headaches.

Dr.Camel's Conclusion

This research provides valuable insights into the potential benefits of TCAs in managing tension-type headaches. While TCAs have shown promise, it's important to note that they are not a cure-all. The study also highlights the need for further research into effective treatment strategies for chronic tension-type headaches. Remember, just as a traveler in the desert needs to be prepared for the journey, those with tension-type headaches should seek professional guidance and develop a personalized management plan.
Date :
  1. Date Completed 2018-07-03
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

28721535

DOI: Digital Object Identifier

PMC5698213

Related Literature

Article Analysis
・Effective treatment of headache
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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