Paper Details

  1. Home
  2. Paper Details

Potential New Non-Invasive Therapy Using Artificial Oxygen Carriers for Pre-Eclampsia.

Author: KagaMaiko, LiHeng, OhtaHidenobu, OkamuraKunihiro, SakaiHiromi, YaegashiNobuo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Hemoglobin vesicles (HbV) were found to be a potential therapy for pre-eclampsia by rescuing placental ischemia. In a rat model, HbV treatment reduced maternal sFlt-1 levels and improved fetal growth restriction. These findings suggest that HbV could be a safe and effective noninvasive therapy for pre-eclampsia.
Paper Details　
Original Abstract of the Article :
The molecular mechanisms of pre-eclampsia are being increasingly clarified in animals and humans. With the uncovering of these mechanisms, preventive therapy strategies using chronic infusion of adrenomedullin, vascular endothelial growth factor-121 (VEGF-121), losartan, and sildenafil have been pro...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618283/

データ提供：米国国立医学図書館（NLM）

Pre-Eclampsia: A New Path to Treatment with Artificial Oxygen Carriers

The [challenges of pre-eclampsia] are a concern for pregnant women, potentially impacting both the mother and the developing fetus. This research explores a [novel approach] to treating pre-eclampsia using [artificial oxygen carriers (HbV)]. This new strategy aims to address the underlying cause of pre-eclampsia, [placental ischemia], by directly delivering oxygen to the placenta.

Artificial Oxygen Carriers: A Potential Breakthrough for Pre-Eclampsia Treatment

The study demonstrates that HbV can effectively [rescue placental and fetal hypoxia], leading to improved fetal growth. This suggests that HbV could be a promising treatment for pre-eclampsia, potentially reducing the need for [C-sections] and improving outcomes for both mother and baby.

A New Hope for Pre-Eclampsia: A Non-Invasive Approach

This research offers a glimpse into the future of pre-eclampsia treatment. The potential of HbV to [deliver oxygen directly to the placenta] could revolutionize how we manage this condition, providing a non-invasive and potentially more effective alternative to existing therapies.

Dr.Camel's Conclusion

This research is like a [desert bloom] in the challenging landscape of pre-eclampsia, offering a potential new treatment strategy. The findings suggest that HbV could be a [game-changer] in managing this condition, potentially improving outcomes for both mother and baby.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28758949

DOI: Digital Object Identifier

PMC5618283

Related Literature

Article Analysis
・Side Effects of losartan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.