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Comparative tolerability of labetalol versus propranolol, atenolol, pindolol, metoprolol, and nadolol.

Author: BurrisJ F, GoldsteinJ, PlachetkaJ R, SirgoM A, SuttonJ M, ZagerP G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Labetalol was found to be well-tolerated in patients with hypertension who had previously experienced side effects from beta-blocker therapy. 88% of patients preferred labetalol to their previous beta-blocker therapy, with the most common new side effect being dizziness in 3 patients. Labetalol controlled blood pressure in 88% of patients.
Paper Details　
Original Abstract of the Article :
The side-effect profile of labetalol was assessed in 34 patients with mild to moderate essential hypertension who had previously experienced side effects during beta-blocker therapy. The most frequently reported beta-blocker side effects were fatigue, impotence, cold extremities, and depression. Aft...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2878065

データ提供：米国国立医学図書館（NLM）

Labetalol: A Potential Alternative to Conventional Beta-Blockers

Beta-blockers are a mainstay in the treatment of hypertension, but they can sometimes cause unpleasant side effects. This study explores the tolerability of labetalol, a unique beta-blocker, compared to conventional beta-blockers in patients experiencing side effects. The researchers compared the side effect profiles of labetalol and several conventional beta-blockers in a group of patients with hypertension. Their findings provide valuable insights into the relative tolerability of these drugs.

Labetalol's Promise: A More Tolerable Option for Hypertension

The study found that labetalol was generally well-tolerated, with fewer side effects compared to conventional beta-blockers. This research suggests that labetalol may be a suitable alternative for patients who experience side effects with traditional beta-blockers. The researchers also found that labetalol effectively controlled blood pressure in most patients, demonstrating its efficacy as an antihypertensive agent.

Labetalol: A Potential Solution for Patients Experiencing Side Effects from Conventional Beta-Blockers

This study suggests that labetalol may be a more tolerable option for patients experiencing side effects from conventional beta-blockers. Its unique properties, including its dual beta- and alpha-blocking activity, may contribute to its favorable side effect profile. Like a camel navigating a scorching desert, labetalol may provide a cooler, more comfortable journey for some patients with hypertension. This research provides valuable insights for clinicians seeking to optimize patient care and minimize side effects.

Dr.Camel's Conclusion

This study highlights the potential benefits of labetalol as a more tolerable alternative to conventional beta-blockers. Its unique properties and favorable side effect profile may make it a suitable option for patients experiencing side effects from traditional beta-blockers. Remember, a wise camel always seeks the path with the most comfortable terrain, just as clinicians strive to find the best treatment options for their patients.

Date :
  1. Date Completed 1987-01-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2878065

DOI: Digital Object Identifier

2878065

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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