Glycemic effects of quinine infusion in healthy volunteers.

Author: MbanyaJean-Claude, NjomatchouaAudrey Carine, SobngwiEugene, TankeuAurel Tiakouang

Paper Details 
Original Abstract of the Article :
BACKGROUND: We aimed to quantify the glycemic effects of quinine in healthy individuals. METHODS: We evaluated the glycemic profile in response to 4 h infusion of 500 ml of 0.9% saline versus 5% glucose solution with and without quinine at therapeutic dose (500 mg) in ten healthy volunteers (8 men)...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571493/

データ提供:米国国立医学図書館(NLM)

Quinine Infusion and Blood Glucose: A Desert Oasis with a Twist

Quinine, a well-known antimalarial drug, is like a desert oasis, providing relief from the harshness of malaria. This study delves into the unexpected effects of quinine infusion on blood glucose levels in healthy individuals. The researchers found that quinine infusion at therapeutic doses resulted in a mild drop in blood glucose levels, particularly during the first hour of infusion. This finding is important because it highlights the potential for quinine to induce hypoglycemia, a condition where blood sugar levels drop too low. Think of it like a camel finding a mirage in the desert, a deceptive illusion that can lead to dehydration.

A Balancing Act: Quinine and Blood Glucose

This study demonstrates that quinine can have a significant impact on blood glucose levels, even in healthy individuals. Think of it like a delicate balance between the desert's harsh sun and the oasis's refreshing water. The researchers found that quinine infusion led to a mild drop in blood glucose levels, potentially putting individuals at risk of hypoglycemia. This finding underscores the importance of monitoring blood glucose levels closely, particularly during the first hour of quinine infusion.

Navigating the Desert: Understanding Quinine's Effects

This study highlights the importance of understanding the potential side effects of medications, even those that are generally considered safe. Think of it like a camel navigating a desert, aware of the dangers that lie ahead. Quinine, while effective for treating malaria, can have a significant impact on blood glucose levels. This finding underscores the need for careful monitoring of patients receiving quinine, particularly those at risk of hypoglycemia.

Dr.Camel's Conclusion

This study reminds us that even familiar medications can have unexpected effects. It's a reminder that we must constantly be learning and adapting, just like a camel traversing the vast and ever-changing desert landscape.

Date :
  1. Date Completed 2018-05-07
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28836995

DOI: Digital Object Identifier

PMC5571493

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Languages

English

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