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Efficacy and safety of doxazosin in hypertension therapy.

Author: HaydukK

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Doxazosin, an alpha-blocker, was found to be effective in lowering blood pressure, with a favorable lipid profile and comparable side effects to placebo, suggesting its potential for treating hypertension.
Paper Details　
Original Abstract of the Article :
In double-blind, controlled, parallel, comparative trials, the blood pressure-lowering effect of doxazosin was compared with that of placebo and other active agents. In 1 large, multicenter study, 903 patients were evaluated: 408 patients received doxazosin; 323, active comparative agents (nadolol, ...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9149(87)90155-x

データ提供：米国国立医学図書館（NLM）

Doxazosin: A Smooth Operator for High Blood Pressure

High blood pressure is a common concern, and finding the right treatment is like finding a reliable camel for a long desert trek. This research examines the effectiveness of [doxazosin] in treating [hypertension]. The authors conducted [double-blind, controlled, parallel, comparative trials] to compare the effects of doxazosin to [placebo] and other [active agents]. These studies revealed that doxazosin, when used as [monotherapy], can [effectively lower blood pressure] without significantly affecting heart rate. It's like finding a reliable oasis that provides hydration without disturbing the desert's calm.

Effective and Well-Tolerated

Doxazosin showed [significant reductions] in both [systolic] and [diastolic blood pressure] compared to baseline and placebo. The study also indicated that doxazosin has a [favorable lipid profile], which is like a camel having a healthy diet of nutritious desert plants.

Finding the Right Oasis

This research underscores the potential of doxazosin as a treatment option for high blood pressure. It's like a reliable camel, providing a smooth and safe journey through the desert of hypertension. However, it's crucial to consult a medical professional to determine if doxazosin is the right treatment for you.

Dr. Camel's Conclusion

Doxazosin has proven itself to be a valuable tool in the fight against high blood pressure. Like a calm and steady camel, it can help navigate the challenges of this condition with minimal side effects. It's a promising oasis in the desert of hypertension management.

Date :
  1. Date Completed 1987-06-26
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

2884851

DOI: Digital Object Identifier

10.1016/0002-9149(87)90155-x

Related Literature

Article Analysis
・Side Effects of nadolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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