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Newer antiepileptic drugs compared to levetiracetam as adjunctive treatments for uncontrolled focal epilepsy: An indirect comparison.

Author: ChenDeng, LiuLing, TanGe, WangHai-Jiao, XuDa, ZhuLi-Na

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This study aims to compare the efficacy and tolerability of newer antiepileptic drugs (AEDs), including eslicarbazepine (ESL), lacosamide (LAC), perampanel (PER), and brivaracetam (BRV), to levetiracetam (LEV) when used as add-on treatments for uncontrolled focal epilepsy.
Paper Details　
Original Abstract of the Article :
Newer antiepileptic drugs (AEDs), such as Eslicarbazepine (ESL), Lacosamide (LAC), Perampanel (PER) and Brivaracetam (BRV), have been marketed as adjunctive treatments for partial-onset seizures. Our aim was to compare the efficacy and tolerability of newer AEDs with Levetiracetam (LEV), when used a...See full text at original site
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引用元：
https://doi.org/10.1016/j.seizure.2017.07.017

データ提供：米国国立医学図書館（NLM）

A Comparison of Antiepileptic Drugs: A Desert of Choices

Epilepsy, like a sudden sandstorm in the desert, can disrupt the normal flow of life. This study compared the efficacy and tolerability of newer antiepileptic drugs (AEDs) with levetiracetam, used as add-on treatments for uncontrolled focal epilepsy. Imagine a caravan of camels, each carrying a different type of remedy for battling the desert sandstorms.

The researchers compared the effectiveness of Eslicarbazepine (ESL), Lacosamide (LAC), Perampanel (PER), Brivaracetam (BRV), and Levetiracetam (LEV) in controlling focal epilepsy. It's like comparing the different remedies each camel has in their pack, to see which one works best against the sandstorm.

Navigating the Right Path

This research provides valuable information for clinicians seeking to find the most effective AED for their patients with uncontrolled focal epilepsy. It's like choosing the right camel with the most suitable remedy to navigate the turbulent sandstorms of epilepsy.

Finding the Best Remedy

The researchers aimed to determine which newer AEDs might be more effective and tolerable than Levetiracetam. They carefully examined the effectiveness of each drug, like comparing the different remedies to find the most effective solution for battling the sandstorm.

Dr. Camel's Conclusion

This study provides a valuable guide for navigating the complex terrain of epilepsy treatment. It's like having a map of the desert, guiding us towards the most effective treatments for our patients. The research underscores the importance of personalized medicine in epilepsy care, ensuring that patients receive the best possible treatment tailored to their individual needs.

Date :
  1. Date Completed 2018-06-15
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

28854405

DOI: Digital Object Identifier

10.1016/j.seizure.2017.07.017

Related Literature

Article Analysis
・Effective treatment of epilepsy
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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