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Successful treatment of bilateral endogenous Fusarium solani endophthalmitis in a patient with acute lymphocytic leukaemia.

Author: BertacciniPatrizia, CastagnettiFausto, CavoMichele, FaccioliLuca, LewisRussell E, PaolucciMichela, PrimaveraLaura, RizzelloIlaria, SpinardiLuca, StanzaniMarta, ToschiPier Giorgio

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A patient with acute lymphoblastic leukemia developed disseminated Fusarium solani infection despite posaconazole prophylaxis. She was successfully treated with a combination of liposomal amphotericin B and voriconazole, as well as intraocular injections of voriconazole and topical amphotericin B.
Paper Details　
Original Abstract of the Article :
Fusarium spp. are an uncommon cause of fungaemia in immunocompromised and neutropenic patients that may hematogenously disseminate to the eyes. Herein, we describe a patient with acute lymphoblastic leukaemia and a prior history of extensive corticosteroid exposure who developed disseminated Fusariu...See full text at original site
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引用元：
https://doi.org/10.1111/myc.12697

データ提供：米国国立医学図書館（NLM）

Combating the Desert Storm of Fusarium Endophthalmitis

Immunocompromised individuals often face a heightened risk of opportunistic infections. This study focuses on a patient with acute lymphoblastic leukaemia who developed disseminated Fusarium solani infection, a rare fungal infection that can spread to the eyes. The patient received combination therapy with liposomal amphotericin B and voriconazole, along with intraocular injections and topical treatments. The case highlights the challenges of managing this challenging fungal infection in immunocompromised patients.

A Successful Battle Against Fusarium

Despite the patient's weakened immune system and prior history of extensive corticosteroid exposure, the combination therapy proved successful in managing the disseminated Fusarium solani infection. The case report demonstrates the importance of multidisciplinary approaches and aggressive treatment strategies in addressing complex infections in immunocompromised individuals.

Navigating the Immune System's Landscape

The immune system's landscape is complex and can be vulnerable to invasion by opportunistic infections. This study underscores the need for careful monitoring and prompt intervention in immunocompromised patients. Understanding the challenges of managing fungal infections in these individuals is crucial for navigating the complexities of their healthcare needs.

Dr. Camel's Conclusion

This study illustrates the importance of navigating the complex terrain of the immune system, especially in the face of opportunistic infections. It highlights the strength and resilience of the human body, showcasing the effectiveness of multidisciplinary care in combating even the most challenging infections.

Date :
  1. Date Completed 2018-08-17
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

28872724

DOI: Digital Object Identifier

10.1111/myc.12697

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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