The effects of cefotetan disodium on haemostasis.

Author: BaxR, CohenH, MachinS J, MackieI J, MoulsdaleM, PozniakA, ShearerM, WalsheK

Paper Details 
Original Abstract of the Article :
A 7-day course of intravenous cefotetan disodium was given to nine patients. No significant changes were observed in haematological or biochemical parameters and serum vitamin K1 levels, prothrombin times, factor VII levels, thrombin times and activated partial thromboplastin times remained within t...See full text at original site
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引用元:
https://doi.org/10.1016/0195-6701(87)90032-6

データ提供:米国国立医学図書館(NLM)

Cefotetan Disodium: Navigating the Hemostatic Desert

Cefotetan disodium, a potent antibiotic, is often used to combat bacterial infections. This study delves into the potential impact of cefotetan disodium on the delicate balance of hemostasis, the process of blood clotting. Researchers, like explorers navigating a vast desert landscape, meticulously monitored the effects of a 7-day course of intravenous cefotetan disodium on nine patients. Their findings reveal a curious twist: while cefotetan disodium did not significantly alter most hemostatic parameters, it did lead to a slight prolongation of bleeding time in two patients, suggesting a potential for increased bleeding risk.

A Desert Oasis of Hemostatic Balance: Understanding Cefotetan Disodium's Effects

This study provides valuable insights into the potential impact of cefotetan disodium on hemostasis. The findings highlight the need to carefully monitor patients receiving this antibiotic, especially those with pre-existing bleeding disorders or deficiencies in vitamin K1. Prophylactic administration of vitamin K1 may be necessary to mitigate potential bleeding risks, ensuring a smooth and safe passage through the desert of antibiotic therapy.

Navigating the Hemostatic Desert: Staying Alert to Potential Risks

The desert of hemostasis can be a treacherous terrain, and the use of cefotetan disodium, like a sudden sandstorm, can disrupt this delicate balance. This study serves as a valuable guide, reminding clinicians to be vigilant in monitoring patients receiving this antibiotic. By understanding the potential risks and taking appropriate precautions, we can navigate this terrain with greater awareness and ensure the safety of our patients.

Dr. Camel's Conclusion

This study explores the impact of cefotetan disodium on hemostasis, revealing a potential for increased bleeding risk in some patients. By understanding the potential risks and taking appropriate precautions, such as monitoring patients carefully and administering prophylactic vitamin K1, we can navigate this terrain with greater awareness and ensure the safety of our patients.

Date :
  1. Date Completed 1987-10-27
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2888812

DOI: Digital Object Identifier

10.1016/0195-6701(87)90032-6

Related Literature

SNS
PICO Info
in preparation
Languages

English

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