Oral Ingestion and Intraventricular Injection of Curcumin Attenuates the Effort-Related Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Motivational Symptoms of Depression.

Author: BognerRobin H, CollinsSamantha, CorreaMerce, GorkaDea, ManchandaArushi, MistryAnisha, QianEmily, SalamoneJohn D, YohnSamantha E

Paper Details 
Original Abstract of the Article :
Effort-related choice tasks are used for studying depressive motivational symptoms such as anergia/fatigue. These studies investigated the ability of the dietary supplement curcumin to reverse the low-effort bias induced by the monoamine storage blocker tetrabenazine. Tetrabenazine shifted effort-re...See full text at original site
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引用元:
https://doi.org/10.1021/acs.jnatprod.7b00425

データ提供:米国国立医学図書館(NLM)

Curcumin: A Potential Oasis in the Desert of Depression

Depression is a complex and often debilitating condition, characterized by feelings of sadness, hopelessness, and a loss of motivation. This study explores the potential of curcumin, a natural compound found in turmeric, to alleviate motivational symptoms associated with depression. The researchers used a model of effort-related choice tasks, investigating the effects of curcumin on the low-effort bias induced by tetrabenazine, a medication that blocks the storage of monoamines. They found that curcumin effectively reversed the negative effects of tetrabenazine, suggesting its potential as a therapeutic agent for treating motivational symptoms of depression.

A Glimmer of Hope: Curcumin’s Potential for Treating Motivational Symptoms of Depression

This research provides promising evidence for the therapeutic potential of curcumin in addressing motivational symptoms of depression, a debilitating condition that can leave individuals feeling drained and apathetic. Just as a camel relies on its innate motivation to traverse the vast and challenging desert, individuals struggling with depression need to regain their motivation to overcome their challenges. The study’s findings offer a ray of hope, suggesting that curcumin could play a role in restoring this vital drive and helping individuals reclaim their lives.

Unlocking Motivation: Exploring the Potential Benefits of Curcumin for Depression

This research encourages further exploration of curcumin’s potential as a therapeutic agent for treating motivational symptoms associated with depression. It’s a reminder that natural compounds can hold valuable therapeutic properties, offering a potential path to relief for individuals struggling with this challenging condition. While further studies are needed to confirm its effectiveness in humans, this research provides a promising foundation for developing novel treatments and exploring the potential of natural remedies for mental health challenges.

Dr. Camel's Conclusion

This research offers a glimmer of hope in the desert of depression, suggesting that curcumin could be a valuable tool in addressing motivational symptoms. It’s a reminder that nature often holds the key to healing, and we can learn much from the wisdom of traditional remedies. While more research is needed, this study provides a promising starting point for exploring the therapeutic potential of curcumin and its potential to bring relief to those struggling with depression.

Date :
  1. Date Completed 2017-11-24
  2. Date Revised 2019-01-03
Further Info :

Pubmed ID

28905625

DOI: Digital Object Identifier

10.1021/acs.jnatprod.7b00425

Related Literature

SNS
PICO Info
in preparation
Languages

English

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