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The Dose-Dependent Effects of Ketoprofen on Dynamic Pain after Open Heart Surgery.

Author: BibouletClaire, BobyHenri, DualeChristian, EljeziVedat, PereiraBruno, SchoefflerPierre

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intravenous ketoprofen at a standard dose of 0.5 mg/kg every 6 hours effectively reduced dynamic and static postoperative pain after open heart surgery, without any negative effects on tolerance outcomes. Lower doses of ketoprofen were not effective in reducing pain.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) can reduce postoperative pain, in both static (i.e., at rest) and dynamic contexts (e.g., during coughing or mobilization), and reduced doses could improve their efficacy/tolerance balance. OBJECTIVES: To test this hypothesis of efficacy af...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/28934782

データ提供：米国国立医学図書館（NLM）

Ketoprofen: A Dose of Relief After Open Heart Surgery

This research delves into the complex world of postoperative pain management, specifically exploring the use of ketoprofen, a non-steroidal anti-inflammatory drug (NSAID), after open heart surgery. Think of it like finding a way to soothe a camel's aches and pains after a grueling journey through a harsh desert. This randomized, double-blind trial compared different doses of intravenous ketoprofen, seeking to determine the optimal dosage that effectively reduces pain while minimizing potential side effects.

Finding the Right Balance

The study found that only the full-dose ketoprofen group experienced significant reductions in both dynamic and static postoperative pain compared to placebo. This is like finding a wellspring of pain relief in the desert, offering a powerful solution to the discomfort following surgery. The study also revealed that ketoprofen did not negatively impact postoperative morphine consumption or tolerance outcomes, suggesting a favorable safety profile.

A Journey Through Recovery

Recovering from open heart surgery can be a challenging journey, like navigating a treacherous desert landscape. This research offers valuable insights into pain management strategies, highlighting the potential benefits of ketoprofen while emphasizing the importance of individualizing dosage based on patient needs. Always discuss your pain management options with your surgeon and anesthesiologist, finding the right path to a smooth and comfortable recovery.

Dr.Camel's Conclusion

This study underscores the importance of finding the right balance in postoperative pain management. It's like navigating a desert with limited resources, carefully choosing the best strategy to ensure a comfortable and successful journey through recovery. By understanding the complexities of pain management and working closely with your healthcare providers, you can find the right path to a smoother and more comfortable recovery.

Date :
  1. Date Completed 2018-06-08
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

28934782

DOI: Digital Object Identifier

28934782

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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