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Tolerability and efficacy of colestipol hydrochloride for accelerated elimination of teriflunomide.
Author: AungstAngela, CasadyLise, DixonCrystal, MaldonadoJanice, McCoyBradlee, MoreoNatalie, RobertsonDerrick
Original Abstract of the Article :
Teriflunomide is an oral disease modifying therapy approved for the treatment of relapsing forms of multiple sclerosis. Teriflunomide' s pharmacokinetics (PK) contribute to its slow elimination, on average taking 6-8 months, though it can take up to 2 years in some instances. This slow elimination c...See full text at original site
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引用元:
https://doi.org/10.1080/17512433.2017.1395280
データ提供:米国国立医学図書館(NLM)
Accelerating the Elimination of Teriflunomide: A New Approach for Multiple Sclerosis
Multiple sclerosis (MS) is a complex and challenging neurological disorder, with researchers continually seeking new and effective treatments. This research focuses on teriflunomide, an oral disease-modifying therapy approved for relapsing forms of MS. The study examines the challenges associated with teriflunomide's slow elimination, highlighting the need for accelerated elimination procedures (AEPs) in certain clinical situations, such as during pregnancy. The authors discuss the current limitations of AEPs using oral cholestyramine or activated charcoal, emphasizing the need for alternative approaches with improved tolerability and administration routes. This research underscores the importance of optimizing treatment strategies for MS, ensuring patient safety and minimizing the impact of medication side effects.
Navigating the Desert of MS Treatment: Seeking New Solutions
The desert of MS treatment is a complex and ever-changing landscape, with researchers continually seeking new solutions to address the challenges of this debilitating disorder. This research explores the need for accelerated elimination procedures for teriflunomide, highlighting the importance of optimizing treatment strategies to ensure patient safety and minimize the impact of medication side effects. It's a reminder that the desert of MS research is a dynamic one, with ongoing efforts to find new and improved treatments to manage this complex condition.
A New Oasis in the Desert of MS Treatment: Accelerated Elimination of Teriflunomide
The desert of MS treatment is a challenging landscape to navigate, with its complexities and uncertainties. This research highlights the need for accelerated elimination procedures for teriflunomide, providing a potential oasis of relief for patients facing certain clinical situations. The study's findings underscore the importance of ongoing research to optimize treatment strategies, enhancing patient safety and minimizing the impact of medication side effects.
Dr.Camel's Conclusion
This research provides valuable insights into the need for optimized treatment strategies for MS, particularly regarding teriflunomide's slow elimination. The search for new and improved AEPs is ongoing, with the goal of enhancing patient safety and minimizing the impact of medication side effects. It's a reminder that the desert of MS research is a dynamic one, with researchers constantly striving to find better solutions for those navigating this complex condition.
Date :
- Date Completed 2017-12-13
- Date Revised 2021-12-04
Further Info :
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