Cardiovascular effects of premedication with medetomidine alone and in combination with MK-467 or glycopyrrolate in dogs subsequently anesthetized with isoflurane.

Author: BennettRachel C, KuuselaErja, RaekallioMarja R, SallaKati M, ScheininMika, TunsCosmin I, VainioOuti M

Paper Details 
Original Abstract of the Article :
OBJECTIVE To compare cardiovascular effects of premedication with medetomidine alone and with each of 3 doses of MK-467 or after glycopyrrolate in dogs subsequently anesthetized with isoflurane. ANIMALS 8 healthy purpose-bred 5-year-old Beagles. PROCEDURES In a randomized crossover study, each dog r...See full text at original site
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引用元:
https://doi.org/10.2460/ajvr.78.11.1245

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Anesthesia: A Balancing Act of Cardiovascular Effects

The desert of [anesthesia] requires careful navigation, with a constant need to balance [cardiovascular effects] of different medications. This study investigates the cardiovascular effects of premedication with [medetomidine] alone and in combination with [MK-467] or [glycopyrrolate] in dogs subsequently anesthetized with [isoflurane]. The researchers discovered that [MK-467] effectively counteracted the hemodynamic changes induced by [medetomidine], suggesting that this combination could be a safer and more effective premedication strategy. The study's findings are valuable for veterinarians seeking to optimize cardiovascular stability in dogs undergoing anesthesia.

The Oasis of Cardiovascular Stability: Finding the Right Balance

The study highlights the importance of choosing the right premedication regimen for dogs undergoing anesthesia. The findings suggest that combining [medetomidine] with [MK-467] could provide a more stable cardiovascular profile compared to [medetomidine] alone. This insight is crucial for veterinarians aiming to minimize cardiovascular risks during anesthesia and ensure the safety of their patients.

Living in the Oasis: Anesthesia for Our Canine Companions

The desert of [anesthesia] can be a complex landscape for both dogs and their owners. This study sheds light on the importance of choosing the right premedication regimen for our canine companions. Consulting with a veterinarian to discuss your dog's individual needs and risks is essential before any anesthesia procedure. The journey through the desert of [anesthesia] can be made smoother with the right guidance and care.

Dr.Camel's Conclusion

The desert of [anesthesia] requires a delicate balance of medications and careful monitoring. This study helps veterinarians navigate this challenging landscape by providing valuable insights into the cardiovascular effects of different premedication combinations. It's a reminder that finding the right balance for each individual patient is key to ensuring a safe and successful anesthesia experience.

Date :
  1. Date Completed 2018-02-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

29076369

DOI: Digital Object Identifier

10.2460/ajvr.78.11.1245

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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