A Systematic Review of Atypical Antipsychotics in Chronic Pain Management: Olanzapine Demonstrates Potential in Central Sensitization, Fibromyalgia, and Headache/Migraine.

Author: CovingtonEdward C, JimenezXavier F, SundararajanTharani

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Many psychopharmacologic agents are used as primary or adjuncts in pain management. Atypical antipsychotics (AAs) have also been used as adjuncts in pain management regimens in a variety of manners; however, their efficacy in this capacity is unclear. METHODS: A systematic review of a...See full text at original site
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引用元:
https://doi.org/10.1097/AJP.0000000000000567

データ提供:米国国立医学図書館(NLM)

Atypical Antipsychotics for Pain Management: A Camel's Perspective

Chronic pain can be a debilitating condition, impacting every aspect of life. Doctors often turn to various medications to manage chronic pain, and atypical antipsychotics (AAs) have shown promise in specific pain syndromes. This study conducted a systematic review of existing research examining the use of AAs for pain management. The researchers delved into the available data, focusing on the efficacy of various AAs, including olanzapine, quetiapine, risperidone, aripiprazole, ziprasidone, clozapine, paliperidone, iloperidone, and lurasidone, in managing pain syndromes.

Olanzapine Emerges as a Potential Treatment Option

The review found that olanzapine demonstrated promising preliminary evidence of efficacy in managing fibromyalgia and headache/migraine. While more research is needed, these findings suggest that olanzapine may offer a potential treatment option for these specific pain syndromes. However, it's important to note that the evidence for other AAs in pain management remains inconclusive.

Navigating Chronic Pain: What This Means for You

If you're struggling with chronic pain, it's essential to work with your doctor to develop a personalized pain management plan. This study provides valuable insights into the potential benefits of olanzapine, but it's crucial to consult with your doctor to determine the most appropriate treatment options. Remember, managing chronic pain requires a multifaceted approach, which may include medication, lifestyle changes, and other therapies.

Dr. Camel's Conclusion

This study highlights the potential of AAs in pain management, particularly olanzapine, for treating specific pain syndromes. However, more research is needed to understand the full therapeutic potential of these medications. As we continue to explore new ways to manage chronic pain, we may find that nature's own remedies hold valuable answers.

Date :
  1. Date Completed 2019-08-06
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

29077621

DOI: Digital Object Identifier

10.1097/AJP.0000000000000567

Related Literature

SNS
PICO Info
in preparation
Languages

English

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