Two Phase 1, Open-Label, Single-Dose, Randomized, Crossover Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered Granules of Secnidazole (2 g) in Healthy Female Volunteers Under Different Administration Conditions.

Author: AdetoroNikki, PentikisHelen S

Paper Details 
Original Abstract of the Article :
Bacterial vaginosis (BV) is the most common vaginal infection in reproductive-age women and a significant risk factor for sexually transmitted diseases and pregnancy complications. Standard 5- to 7-day antimicrobial treatments for BV are associated with high rates of recurrence and adverse events. S...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033001/

データ提供:米国国立医学図書館(NLM)

Secnidazole Granules: A New Route Through the Desert of Bacterial Vaginosis

The realm of gynecology is like a vast desert with various challenges, and bacterial vaginosis (BV), a common vaginal infection, is a particularly stubborn dune. This study, my dear readers, is like a group of explorers testing a new treatment for BV, a novel granule formulation of secnidazole, SYM-1219, that aims to provide a safe and effective single-dose treatment. The researchers are examining the pharmacokinetics, safety, and tolerability of this new formulation.

A New Oasis for Bacterial Vaginosis: Exploring the Potential of Secnidazole Granules

This research is like a caravan equipped with a new and improved compass, navigating towards a more effective treatment for BV. The researchers discovered that SYM-1219, a novel granule formulation of secnidazole, demonstrated good pharmacokinetic properties and a favorable safety profile.

Navigating the Desert of Vaginal Infections: A New Treatment Option for Bacterial Vaginosis

As a camel, I've always appreciated the value of a well-equipped caravan. This research is like a group of scientists testing a new and improved solution for BV, a common vaginal infection. The findings suggest that SYM-1219 could provide a convenient and effective treatment option, potentially leading to better outcomes for women suffering from this condition.

Dr. Camel's Conclusion

This research is a beacon of hope in the desert of vaginal infections, offering a potential new treatment option for bacterial vaginosis. The authors' investigation of secnidazole granules, SYM-1219, demonstrates promising results, paving the way for a more convenient and effective treatment approach.

Date :
  1. Date Completed 2019-09-16
  2. Date Revised 2019-09-16
Further Info :

Pubmed ID

29125715

DOI: Digital Object Identifier

PMC6033001

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.