Effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs on the incidence of recurrent colorectal adenomas: a systematic review with meta-analysis and trial sequential analysis of randomized clinical trials.

Author: ChaiyakunaprukNathorn, ChingSiew Mooi, LimKean Ghee, PhisalprapaPochamana, SaokaewSurasak, VeettilSajesh K

Paper Details 
Original Abstract of the Article :
Beneficial effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) against recurrent colorectal adenomas have been documented in systematic reviews; however, the results have not been conclusive. Uncertainty remains about the appropriate dose of aspirin for adenoma preventio...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686945/

データ提供:米国国立医学図書館(NLM)

Aspirin and NSAIDs: A Closer Look at Colorectal Adenoma Prevention

This systematic review and meta-analysis explores the potential of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) in preventing recurrent colorectal adenomas. The study synthesizes data from numerous randomized clinical trials, examining the efficacy of these medications in reducing the risk of adenoma recurrence. While previous research has suggested beneficial effects of aspirin and NSAIDs, the authors find that the results are not entirely conclusive. The study also highlights the need for further research to determine the optimal dose of aspirin for adenoma prevention and to understand the persistence of the protective effect of NSAIDs after treatment cessation.

Navigating Colorectal Adenoma Prevention: A Critical Review

This research provides a comprehensive overview of the evidence regarding the use of aspirin and NSAIDs in preventing recurrent colorectal adenomas. While the study suggests potential benefits, it acknowledges that more research is needed to confirm their effectiveness. The study emphasizes the importance of carefully considering the risks and benefits of these medications before making treatment decisions. This research highlights the complexities of cancer prevention and the need for ongoing scientific inquiry to refine our understanding of these preventive measures.

Preventing Colorectal Adenomas: Understanding the Risks and Benefits

This research sheds light on the potential role of aspirin and NSAIDs in preventing recurrent colorectal adenomas. While the study suggests possible benefits, it also acknowledges the need for more research to fully understand their effectiveness and to determine the optimal dosage. It's important to consult a healthcare professional to discuss the potential risks and benefits of these medications before making any decisions about their use. Remember, prevention is key when it comes to our health, and understanding the nuances of these medications can help us make informed choices about our well-being.

Dr. Camel's Conclusion

This research reminds us that the quest for preventing colorectal adenomas is a journey through a vast and intricate desert of scientific inquiry. While aspirin and NSAIDs may hold promise, more research is needed to navigate this complex terrain and determine the optimal approach. Just like a camel navigating a treacherous desert, we must be cautious and seek guidance before embarking on any new prevention strategy.

Date :
  1. Date Completed 2018-06-26
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

29137605

DOI: Digital Object Identifier

PMC5686945

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Languages

English

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