Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon.

Author: AllemanLaurent Y, Body-MalapelMathilde, DesreumauxPierre, DingrevilleFlorian, DjouinaMadjid, Gower-RousseauCorinne, Ouali AlamiAdil, PerdrixEsperanza, PichavantMuriel, VignalCécile, WaxinChristophe

Paper Details 
Original Abstract of the Article :
Air pollution is a recognized aggravating factor for pulmonary diseases and has notably deleterious effects on asthma, bronchitis and pneumonia. Recent studies suggest that air pollution may also cause adverse effects in the gastrointestinal tract. Accumulating experimental evidence shows that immun...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700563/

データ提供:米国国立医学図書館(NLM)

Urban Coarse Particles: Breathing in the Desert of Air Pollution

The desert of air pollution is a harsh and unforgiving landscape, posing significant health risks to humans and the environment. This study investigates the effects of inhaling urban coarse particulate matter (PM) on the respiratory and gastrointestinal systems of mice. The researchers sought to understand the impact of these particles on oxidative stress and inflammation in the lungs and colon, examining the potential for the antioxidant N-acetyl-L-cysteine (NAC) to mitigate these effects.

Navigating the Desert of Air Pollution

This study sheds light on the multifaceted impact of air pollution, revealing its potential to affect both the respiratory and gastrointestinal systems. The researchers found that exposure to urban coarse PM induced oxidative stress and inflammation in both the lungs and colon of mice. However, treatment with NAC was able to reverse these effects, suggesting a potential therapeutic role for this antioxidant in mitigating the adverse health consequences of air pollution.

Breathing Easy in the Desert

This research highlights the critical need to address air pollution and its detrimental effects on human health. The findings underscore the importance of reducing exposure to PM and exploring potential therapeutic strategies to mitigate its harmful effects. As we continue to navigate the desert of air pollution, it's essential to prioritize preventive measures and explore innovative solutions to protect human health.

Dr. Camel's Conclusion

This study provides a stark reminder of the dangers lurking in the desert of air pollution. The findings highlight the need for both individual and societal efforts to reduce exposure to PM and explore therapeutic options to mitigate its detrimental effects. It's a journey that requires vigilance, collaboration, and a commitment to creating a healthier environment for all.

Date :
  1. Date Completed 2018-08-27
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29166940

DOI: Digital Object Identifier

PMC5700563

Related Literature

SNS
PICO Info
in preparation
Languages

English

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