Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial.

Author: De LeoVincenzo, Di GiacintoPaola, ExacoustosCaterina, GuccioneLaura, LenziAndrea, MorettiCostanzo, MottaCecilia, PetragliaFelice, SimonelliIlaria, ToscanoVincenzo

Paper Details 
Original Abstract of the Article :
CONTEXT: Hirsutism often occurs in women with polycystic ovary syndrome (PCOS). The efficacy of oral contraceptive pill (OCP) plus antiandrogens in the treatment of its severe expression is controversial due to the lack of randomized, double-blind, long-term studies. OBJECTIVE: The primary outcome ...See full text at original site
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引用元:
https://doi.org/10.1210/jc.2017-01186

データ提供:米国国立医学図書館(NLM)

Treating Severe Hirsutism in PCOS: A New Approach

The world of endocrinology is a vast desert, where researchers constantly seek to understand and treat hormonal imbalances. This study, like a seasoned explorer venturing into this challenging terrain, investigates the effectiveness of a combination therapy, oral contraceptive pills (OCPs) plus bicalutamide, an antiandrogen, in treating severe hirsutism, excessive hair growth, in women with polycystic ovary syndrome (PCOS). Researchers compared the effectiveness of this combination to OCPs alone, hoping to find a more effective treatment for this common and often distressing condition.

The results, like a refreshing oasis in the desert of hirsutism, showed that the combination therapy of OCPs plus bicalutamide was significantly more effective in reducing hirsutism than OCPs alone. While both treatments were effective, the combination therapy provided greater relief from excessive hair growth, offering a more comprehensive solution for women struggling with this condition. This discovery, like a valuable treasure found in the desert, suggests that a targeted approach to treatment, addressing both hormonal imbalances and the effects of excess androgen, may be key to achieving optimal results.

A Multifaceted Approach to Hirsutism Management

This study, like a compass guiding us through the desert of PCOS, highlights the importance of considering a multifaceted approach to managing hirsutism. It encourages healthcare providers to explore a range of treatment options, tailoring them to the individual needs of their patients.

Finding Hope in the Desert of Hormonal Imbalances

The desert of hormonal imbalances can be a challenging place for women with PCOS. This study, like a beacon of hope, provides valuable insights into effective treatment options for hirsutism, offering a path to a more comfortable and confident life.

Dr.Camel's Conclusion

This study, like a camel caravan carrying valuable knowledge, reveals the effectiveness of a combination therapy for treating severe hirsutism in PCOS. It encourages healthcare providers to explore a range of treatment options, offering women with PCOS a greater chance of achieving optimal results and navigating the desert of hormonal imbalances with more confidence.

Date :
  1. Date Completed 2018-06-04
  2. Date Revised 2018-06-04
Further Info :

Pubmed ID

29211888

DOI: Digital Object Identifier

10.1210/jc.2017-01186

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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