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Alzheimer's Disease: A Systemic Review of Substantial Therapeutic Targets and the Leading Multi-functional Molecules.

Author: HodaNasimul, UmarTarana

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Alzheimer's disease (AD) is a fatal brain disorder with no cure. While research has focused on targeting specific areas in the brain, like beta amyloid and cholinesterase, other potential causes, such as tau proteins, inflammation, and gene changes, are also being studied. Current medications mainly target cholinesterase. New drug development is focusing on multi-target approaches that address multiple aspects of the disease. While many promising drugs have been researched, the complexity of the disease makes finding a cure challenging.
Paper Details　
Original Abstract of the Article :
Alzheimer's Disease (AD) is a fatal neurodegenerative disorder, having a complex aetiology with numerous possible drug targets. There are targets that have been known for years while more new targets and theories have also emerged. Beta amyloid and cholinesterases are the most significant biological...See full text at original site
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引用元：
https://doi.org/10.2174/1568026618666180112161024

データ提供：米国国立医学図書館（NLM）

Unraveling Alzheimer's Disease: A Complex Puzzle

Imagine trying to find a lost oasis in a vast, ever-shifting desert. That's what it's like searching for a cure for Alzheimer's disease. This research reviewed promising targets for developing new drugs, highlighting the multifaceted nature of the disease. Many different biological processes are involved, and researchers are diligently working to uncover the secrets behind this debilitating condition. The study emphasized the need for multi-target drugs that can address multiple aspects of the disease simultaneously, like a caravan navigating the desert with various supplies and tools for different challenges.

Multi-Target Approach for Alzheimer's Disease

The review emphasizes the need for a multi-target approach to develop effective treatments for Alzheimer's disease. This highlights the complexity of the disease and the importance of addressing multiple biological processes to potentially achieve a cure.

Hope for the Future

Despite the challenges, the review suggests that there are promising new drug candidates currently being investigated. This offers hope for the future of Alzheimer's disease research and the possibility of finding treatments that can alleviate the suffering caused by this devastating condition.

Dr.Camel's Conclusion

Finding a cure for Alzheimer's disease is like searching for a lost oasis in the vastness of the desert. It's a journey of discovery, filled with intricate details and complex pathways. This research emphasizes the need for a multi-faceted approach, like a well-equipped caravan, to tackle this multifaceted challenge. With ongoing research and innovative strategies, there's hope for a future where we can successfully navigate the sands of Alzheimer's disease and reach a haven of well-being.

Date :
  1. Date Completed 2023-08-19
  2. Date Revised 2023-08-19
Further Info :

Pubmed ID

29332579

DOI: Digital Object Identifier

10.2174/1568026618666180112161024

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Languages

English

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