[The effectiveness of individualized treatment regimen on smear-positive retreatment pulmonary tuberculosis with mono- and poly-drug resistance].

Author: ChenT, DuJ, GaoW W, LiL, LiuY H, LyuX Y, MaY, ShuW, WangH H, XieS H

Paper Details 
Original Abstract of the Article :
<b>Objective:</b> To analyze and evaluate the effectiveness of individualized treatment regimen in the therapy of smear-positive retreatment pulmonary tuberculosis with mono-and poly-drug resistance, and therefor to provide information on how to develop rational individualized regimen for retreatme...See full text at original site
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引用元:
https://doi.org/10.3760/cma.j.issn.1001-0939.2018.01.008

データ提供:米国国立医学図書館(NLM)

Retreatment Tuberculosis: A Complex and Challenging Journey

Tuberculosis (TB) remains a major public health concern worldwide, and retreatment cases, particularly those with drug resistance, present a significant challenge for healthcare providers. This study investigates the effectiveness of individualized treatment regimens for retreatment pulmonary TB cases with mono- and poly-drug resistance. The researchers aimed to compare different treatment approaches, including individualized regimens, intensified retreatment regimens, and standard treatment regimens, to determine which approach offered the best outcomes.

The researchers meticulously analyzed data from a multi-center cohort study that included over 250 retreatment TB cases. They carefully tracked patient outcomes, including treatment success rates, cure rates, and treatment failures, to determine the most effective treatment strategies. It's like navigating a vast desert landscape, seeking to find the most efficient routes for reaching our destination.

Individualized Treatment: A Tailored Approach to Retreatment TB

The study found that individualized treatment regimens were significantly more effective than standard treatment regimens for retreatment TB cases with drug resistance. This finding underscores the importance of tailoring treatment plans to the specific needs of each patient. It's a reminder that the desert of TB treatment is full of diverse challenges, requiring a flexible and adaptable approach. The researchers also observed that higher doses of certain medications and a longer duration of treatment could improve treatment success rates.

Combating Drug Resistance: A Global Effort

This study underscores the ongoing challenge of drug resistance in TB, highlighting the need for continuous research and development of new and more effective treatment options. It's a reminder that the desert of TB is a vast and unforgiving landscape, but with perseverance and collaboration, we can find ways to combat this deadly disease. It's essential to continue investing in research and public health initiatives to control TB and prevent the emergence of drug resistance.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of retreatment tuberculosis, highlighting the importance of individualized care and the need for continued research to combat drug resistance. It's a reminder that the desert of TB treatment is a challenging but rewarding landscape, where innovation and collaboration are essential for finding solutions and improving the lives of those affected.

Date :
  1. Date Completed 2019-02-07
  2. Date Revised 2019-02-15
Further Info :

Pubmed ID

29343012

DOI: Digital Object Identifier

10.3760/cma.j.issn.1001-0939.2018.01.008

SNS
PICO Info
in preparation
Languages

Chinese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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