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Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: a marked improvement in response and survival.

Author: BelangerA, BergeronV, DupontA, EmondJ, GiguereM, LabrieF, LacoursiereY, MonfetteG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 87 patients with stage D2 prostate cancer found that a combination therapy of an antiandrogen and an LHRH agonist was highly effective in achieving remission, improving survival, and maintaining quality of life.
Paper Details　
Original Abstract of the Article :
Eighty-seven previously untreated patients with clinical stage D2 (bone metastases) prostate cancer have received the combination therapy with a pure antiandrogen and an LHRH agonist (or orchiectomy) as first treatment in a multicentre study for up to 34 months (average = 16.2 months). A positive ob...See full text at original site
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引用元：
https://doi.org/10.1016/s0022-4731(85)80024-8

データ提供：米国国立医学図書館（NLM）

Combination Therapy: A Powerful Weapon Against Prostate Cancer

The fight against prostate cancer is a relentless pursuit, with researchers constantly seeking innovative approaches to combat this disease. This study dives deep into the effectiveness of combination therapy, specifically focusing on the use of flutamide and castration for advanced prostate cancer. The authors meticulously analyze the impact of this combined approach, exploring its impact on response rates and overall survival. Their findings suggest that this strategy holds significant promise in improving patient outcomes.

A New Frontier in Prostate Cancer Treatment

The research presents a compelling case for the effectiveness of combination therapy with flutamide and castration in treating advanced prostate cancer. The authors report a remarkable improvement in both response rates and survival rates among patients receiving this treatment. These findings demonstrate the potential of this approach to significantly impact the course of the disease and improve the quality of life for patients.

Hope for a More Effective Treatment

This study sheds light on a promising new treatment approach for advanced prostate cancer, offering hope for improved outcomes and a better quality of life for patients. The combination therapy of flutamide and castration has demonstrated remarkable efficacy in treating this challenging disease, suggesting a new frontier in cancer treatment. This research serves as a testament to the ongoing pursuit of innovative therapies to combat this devastating disease.

Dr.Camel's Conclusion

Prostate cancer, like a stubborn sandstorm, can be relentless. This research presents a beacon of hope, showcasing the potential of combination therapy to effectively combat this disease. The results offer a glimpse of a future where patients can experience a better quality of life and have a greater chance of overcoming this challenging adversary.

Date :
  1. Date Completed 1986-02-14
  2. Date Revised 2019-08-17
Further Info :

Pubmed ID

2934579

DOI: Digital Object Identifier

10.1016/s0022-4731(85)80024-8

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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