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Acute liver failure caused by pembrolizumab in a patient with pulmonary metastatic liver cancer: A case report.

Author: LaiLingling, LiMing, WuZhenping, ZhangLunli, ZhangWenfeng

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

Pembrolizumab (Keytruda) is a PD-1 inhibitor approved for treating advanced melanoma and nonsmall cell lung cancer. Its efficacy and safety in treating advanced liver cancer are still under investigation.
Paper Details　
Original Abstract of the Article :
Keytruda (pembrolizumab) is an inhibitor of programmed cell death receptor-1 (PD-1), which was approved to treat advanced melanoma and nonsmall cell lung cancer patients who do not respond to other treatment. However, its efficacy and security in the treatment of advanced liver cancer is still under...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758274/

データ提供：米国国立医学図書館（NLM）

Pembrolizumab: Exploring the Shifting Sands of Liver Cancer Treatment

The [liver cancer] desert is a vast and treacherous landscape, with [treatment options] often as elusive as a mirage. This study presents a [case report] of [acute liver failure] associated with [pembrolizumab], an [immune checkpoint inhibitor], in a patient with [metastatic liver cancer]. It's like encountering a sudden sandstorm in an otherwise seemingly safe journey.

Pembrolizumab: A Potential Oasis, Yet With Caution

The study emphasizes the need for [caution] in the use of [pembrolizumab] for [advanced liver cancer]. It's like a hidden oasis that can provide relief, but also potentially dangerous. The report underscores the importance of [further research] to understand the [efficacy and safety] of this treatment in [liver cancer].

Navigating the Liver Cancer Desert With Awareness

This research emphasizes the critical role of [ongoing research] and [vigilance] in the treatment of [liver cancer]. It's like being a careful traveler in the desert, always aware of the shifting sands and potential dangers. It reminds us that even the most promising treatments can have unexpected consequences, and that the pursuit of knowledge is essential for navigating this complex disease.

Dr.Camel's Conclusion

The fight against liver cancer is a constant journey through the desert. It's a reminder that we must approach every new treatment with caution, seeking a balance between hope and awareness. As we continue our journey, it's essential to remain vigilant and committed to finding better solutions for those battling this challenging disease.

Date :
  1. Date Completed 2018-02-12
  2. Date Revised 2022-10-05
Further Info :

Pubmed ID

29390572

DOI: Digital Object Identifier

PMC5758274

Related Literature

Article Analysis
・Side Effects of pembrolizumab injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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