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Safety of live vaccines on immunosuppressive or immunomodulatory therapy-a retrospective study in three Swiss Travel Clinics.

Author: BühlerSilja, ChappuisFrançois, EhrenspergerBenoît, EperonGilles, HatzChristoph, HuberFabienne

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Immunosuppressive/immunomodulatory medications allow patients to live similar lifestyles to healthy individuals, including travel. However, live vaccines are generally contraindicated due to the risk of attenuated vaccine microorganism replication. This study investigates the safety of live vaccines in patients on immunosuppressive/immunomodulatory medications.
Paper Details　
Original Abstract of the Article :
Patients increasingly benefit from immunosuppressive/immunomodulatory medications for a range of conditions allowing them a lifestyle similar to healthy individuals, including travel. However, the administration of live vaccines to immunodeficient patients bears the risk of replication of the attenu...See full text at original site
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引用元：
https://doi.org/10.1093/jtm/tax082

データ提供：米国国立医学図書館（NLM）

Immunosuppression and Travel: A Balancing Act

Individuals on immunosuppressive or immunomodulatory therapy face unique challenges when it comes to travel, particularly regarding the administration of live vaccines. These medications weaken the immune system, increasing the risk of complications from live vaccines, as the attenuated virus could potentially replicate. This research delves into the safety of administering live vaccines to immunosuppressed travelers.

The authors conducted a retrospective study to identify travelers seeking pre-travel advice who were on immunosuppressive therapy and received live vaccines. This study provides valuable insights into the practical considerations and potential risks associated with live vaccinations in immunosuppressed individuals.

Navigating the Risks: A Case-by-Case Approach

This research underscores the importance of careful assessment and individual risk-benefit analysis when considering live vaccines for immunosuppressed travelers. The study highlights the need for thorough medical evaluation, including a review of the specific immunosuppressive medication, the intended travel destination, and the potential risks associated with the live vaccine.

Traveling Safely: A Collective Effort

For travelers on immunosuppressive therapy, this research emphasizes the importance of close collaboration with healthcare professionals. It suggests that travelers should consult with their doctors to discuss the appropriate travel vaccines and any potential risks associated with their medication. With careful planning and communication, immunosuppressed individuals can enjoy safe and healthy travels.

Dr.Camel's Conclusion

Just as a camel navigates treacherous desert landscapes, navigating travel while on immunosuppressive therapy requires careful planning and expert guidance. This research serves as a valuable guide, highlighting the importance of individual assessment, risk management, and close communication with healthcare professionals to ensure safe and enjoyable travels.

Date :
  1. Date Completed 2019-07-29
  2. Date Revised 2019-07-29
Further Info :

Pubmed ID

29394383

DOI: Digital Object Identifier

10.1093/jtm/tax082

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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