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Indirect Rotavirus Vaccine Effectiveness for the Prevention of Rotavirus Hospitalization: A Systematic Review and Meta-Analysis.

Author: FlaxmanAbraham D, KhalilIbrahim, MokdadAli H, RosettieKatherine L, TroegerChristopher, VosTheo, WeaverMarcia R

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review assessed the indirect effectiveness of rotavirus vaccines in preventing rotavirus hospitalizations in children under 5 years old. The findings suggest that vaccination provides indirect protection, particularly in high-income countries. Further research is needed to evaluate indirect protection in low- and middle-income countries.
Paper Details　
Original Abstract of the Article :
Two rotavirus vaccines, RotaTeq and Rotarix, are licensed for global use; however, the protection they confer to unvaccinated individuals through indirect effects remains unknown. We systematically reviewed the literature and quantified indirect rotavirus vaccine effectiveness (VE) for preventing ro...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928826/

データ提供：米国国立医学図書館（NLM）

Rotavirus Vaccination: A New Oasis in the Desert of Childhood Infections

Rotavirus, a common cause of severe diarrhea in young children, can be as relentless as a desert sandstorm. This study explores the indirect effects of rotavirus vaccination, examining how vaccination of one child can protect other unvaccinated children from infection. The researchers, like scientists studying the complex dynamics of a desert ecosystem, meticulously analyze data from various studies to determine the effectiveness of indirect protection conferred by rotavirus vaccines. Their goal is to understand the broader impact of vaccination, a powerful tool for combating infectious diseases and protecting vulnerable populations.

A New Path to Herd Immunity

The study reveals that rotavirus vaccines provide significant indirect protection, a phenomenon known as herd immunity. This finding is like a life-giving oasis in the desert, offering a potential path to reducing the burden of rotavirus infection in communities. This research underscores the importance of achieving high vaccination coverage, a crucial step in protecting children from this potentially life-threatening disease. This study encourages continued efforts to increase vaccination rates globally, especially in low- and middle-income countries where rotavirus burden is high.

Navigating the Desert of Childhood Infections

This study, like a beacon of hope in the desert of childhood infections, highlights the powerful impact of vaccination on public health. It reminds us that protecting one child can protect many, a vital concept in combating infectious diseases and ensuring a healthier future for all children. This research underscores the importance of continued investment in vaccination programs, a crucial strategy for navigating the challenging landscape of infectious diseases.

Dr.Camel's Conclusion

This study, like a refreshing spring in the desert, reveals the powerful impact of rotavirus vaccination on both individual and community health. It reminds us that vaccination is a vital tool for protecting children and creating a healthier future for all.

Date :
  1. Date Completed 2019-07-10
  2. Date Revised 2019-07-10
Further Info :

Pubmed ID

29436336

DOI: Digital Object Identifier

PMC5928826

Related Literature

Article Analysis
・Effects of rotavirus vaccine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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