Real life evaluation of safinamide effectiveness in Parkinson's disease.

Author: BorelliniLinda, ComiCristoforo, Di FonzoAlessio, LacerenzaMarco, LazzeriGiulia, ManciniFrancesca, SilaniVincenzo

Paper Details 
Original Abstract of the Article :
In this retrospective study, we evaluated both efficacy and effectiveness of safinamide 50 and 100 mg in the treatment of motor fluctuations and disabling dyskinesias in a cohort of patients with idiopathic Parkinson's disease (PD). Ninety-one PD patients were evaluated during the first year of comm...See full text at original site
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引用元:
https://doi.org/10.1007/s10072-018-3272-y

データ提供:米国国立医学図書館(NLM)

Safinamide's Role in Managing Parkinson's Disease: A Real-World Evaluation

The field of [neurological research] is constantly seeking ways to improve the lives of individuals living with Parkinson's disease (PD). This study examined the real-world effectiveness of safinamide, a medication used to manage motor fluctuations and dyskinesias in PD patients. The researchers analyzed data from 91 PD patients treated with safinamide for a year, evaluating its impact on various aspects of their condition, such as motor function, daily living activities, and medication requirements.

The study demonstrated that safinamide was effective in improving motor complications in PD patients, resulting in a significant reduction in motor fluctuations, dyskinesias, and overall medication dosages. Notably, safinamide was also found to be safe, with only a small number of patients discontinuing treatment due to minor side effects. This finding suggests that safinamide could be a valuable addition to the treatment arsenal for PD patients.

A New Tool for Parkinson's Management

This study offers a real-world perspective on safinamide's effectiveness in managing PD. The findings indicate that safinamide can significantly improve motor symptoms and potentially reduce the need for other medications. While further research is always necessary, this study provides encouraging evidence for the potential benefits of safinamide in improving the quality of life for PD patients.

Living Well with Parkinson's Disease

For individuals living with PD, this study provides a glimmer of hope. Safinamide, like a cool oasis in the desert, can provide respite from the challenges associated with motor fluctuations and dyskinesias. It's important to discuss treatment options with your neurologist to find the best approach for your individual needs and to navigate the journey with Parkinson's disease with strength and resilience.

Dr. Camel's Conclusion

Safinamide's effectiveness in this study is a beacon of hope in the desert of Parkinson's disease. It highlights the importance of ongoing research and development of new treatments to improve the lives of those affected by this complex condition. Like a wise camel guiding a caravan through the desert, safinamide offers a potential path towards better management and a more comfortable journey for PD patients.

Date :
  1. Date Completed 2018-09-06
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29441484

DOI: Digital Object Identifier

10.1007/s10072-018-3272-y

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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