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Sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride: A comprehensive review.

Author: DarwinEvan, FertigRaymond M, GamretA Caresse, GaudiSudeep

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review examines the sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride, commonly used to treat androgenetic alopecia and benign prostatic hyperplasia. Both drugs can increase the incidence of sexual dysfunction, including impotence, decreased libido, and ejaculation disorder. The review compares the sexual side effects associated with different dosages of each drug.
Paper Details　
Original Abstract of the Article :
The 5-α-reductase inhibitors finasteride and dutasteride are frequently used in the treatment of androgenetic alopecia and benign prostatichyperplasia. These drugs are effective at reducing levels of dihydrotestosterone, the primary androgen responsible for the pathogenesis of both these conditions....See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/29447628

データ提供：米国国立医学図書館（NLM）

Exploring the Sexual Side Effects of 5-α-Reductase Inhibitors

The study dives into the complex world of 5-α-reductase inhibitors, commonly used to treat androgenetic alopecia and benign prostatic hyperplasia. The researchers delve into the potential sexual side effects of these medications, comparing the effects of finasteride and dutasteride across different dosages. They aim to provide a comprehensive review of the existing medical literature, offering valuable insights for clinicians and patients alike.

Navigating the Trade-Offs

The study sheds light on the potential for sexual dysfunction, including impotence, decreased libido, and ejaculation disorder, associated with 5-α-reductase inhibitor therapy. This information is crucial for informed decision-making by both patients and healthcare providers. The study's findings suggest a potential trade-off between the benefits of these drugs and their potential side effects.

Informed Decision-Making

Open and honest conversations with healthcare providers about the potential risks and benefits of 5-α-reductase inhibitors are essential. Individuals considering these medications should weigh the potential benefits against the risks and explore alternative treatment options if needed. It's important to remember that everyone responds to medications differently, and individual experiences may vary.

Dr.Camel's Conclusion

This study highlights the importance of understanding the potential sexual side effects associated with 5-α-reductase inhibitors. By carefully considering the risks and benefits, patients and healthcare providers can make informed decisions about the use of these medications. Open communication is crucial to ensuring the best possible outcomes for individual patients.

Date :
  1. Date Completed 2018-04-02
  2. Date Revised 2018-04-02
Further Info :

Pubmed ID

29447628

DOI: Digital Object Identifier

29447628

Related Literature

Article Analysis
・Effects of dutasteride
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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