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Comparison of the Effects of Vonoprazan and Lansoprazole for Treating Endoscopic Submucosal Dissection-Induced Artificial Ulcers.

Author: HaradaSatoshi, HiguchiKazuhide, HiraiAi, KawaguchiShinpei, KojimaYuichi, OtaKazuhiro, TakahashiYoshiaki, TakeuchiToshihisa, TokiokaSatoshi, TominagaKazunari

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Vonoprazan was as effective as lansoprazole in treating ESD-induced ulcers.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Vonoprazan exhibits a more potent, rapid, and longer-lasting inhibitory effect on gastric acid secretion than proton pump inhibitors; however, whether it is more effective than PPI for treating endoscopic submucosal dissection (ESD)-induced artificial ulcers remains controversial. AIM: ...See full text at original site
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引用元：
https://doi.org/10.1007/s10620-018-4948-0

データ提供：米国国立医学図書館（NLM）

A Race to Heal: Vonoprazan vs. Lansoprazole in ESD Ulcers

Endoscopic submucosal dissection (ESD) is a surgical procedure used to treat early gastric neoplasms. This study is a fast-paced race to see which drug, vonoprazan or lansoprazole, is more effective in healing the ulcers that often occur after this procedure. These two drugs are like two racing camels, vying to reach the finish line of ulcer healing.

Neck and Neck in the Healing Race

The study found that both vonoprazan and lansoprazole were [equally effective in healing ESD-induced ulcers]. The healing ratios and shrinkage ratios between the two treatment groups were not significantly different, indicating that both drugs performed well. It's like a close race where both camels cross the finish line almost simultaneously.

A Good News for ESD Patients

These findings offer good news for patients undergoing ESD, as it suggests that [both vonoprazan and lansoprazole are viable options for treating ESD-induced ulcers] . This means that patients can consult with their doctors and choose the drug that is most appropriate for their individual needs.

Dr. Camel's Conclusion

This research is like a thrilling desert race, with both vonoprazan and lansoprazole proving to be equally effective in healing ESD ulcers. While the race is close, the outcome is a win-win for patients, providing them with more choices and greater control over their treatment.

Date :
  1. Date Completed 2018-05-22
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29464587

DOI: Digital Object Identifier

10.1007/s10620-018-4948-0

Related Literature

Article Analysis
・Effects of vonoprazan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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