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Double-blind evaluation of etodolac (200 mg, 400 mg) compared with zomepirac (100 mg) and placebo on third molar extraction pain.

Author: EllisE, ScottR, UptonL G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Etodolac, a non-steroidal anti-inflammatory drug, showed significant analgesic effects in patients with pain compared to placebo. Both 200mg and 400mg doses of etodolac were equally effective and comparable to zomepirac. Both doses were well-tolerated with no serious side effects.
Paper Details　
Original Abstract of the Article :
This controlled, single dose study has demonstrated that compared with placebo, substantial analgesia is obtained with 200 and 400 mg doses of etodolac. The analgesic effects of both doses of etodolac were not notably different from each other or significantly different from zomepirac, a proven anal...See full text at original site
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引用元：
https://doi.org/10.1016/0030-4220(86)90255-0

データ提供：米国国立医学図書館（NLM）

Etodolac for Third Molar Extraction Pain: A Double-Blind Trial

Third molar extraction, also known as wisdom tooth removal, is a common dental procedure that can be associated with significant pain. This research, published in [Journal Name], investigated the effectiveness of etodolac, a nonsteroidal anti-inflammatory drug (NSAID), in managing pain after third molar extraction. The researchers conducted a double-blind study comparing etodolac at two doses (200 mg and 400 mg) to zomepirac, another NSAID, and placebo. They found that both doses of etodolac provided substantial analgesia compared to placebo, with no notable differences between the two doses or compared to zomepirac. The study also found that both doses of etodolac were well tolerated, with no reports of serious or dose-related adverse side effects.

Etodolac Shows Promise for Pain Relief

This research, published in [Journal Name], provides evidence for the effectiveness of etodolac in managing pain after third molar extraction. The study's results suggest that etodolac is a safe and effective alternative to other NSAIDs for this purpose.

Pain Management: A Desert Oasis

Pain can be as relentless as a desert sun, making daily life unbearable. This research, published in [Journal Name], offers hope to those facing post-extraction pain by demonstrating the effectiveness of etodolac, a potential oasis in a desert of discomfort.

Dr.Camel's Conclusion

Just as a camel can endure the heat of the desert, patients undergoing third molar extraction can find relief from pain with etodolac. This research provides valuable insights into the effectiveness and safety of etodolac, offering a beacon of hope to those seeking pain relief.

Date :
  1. Date Completed 1987-02-06
  2. Date Revised 2019-07-12
Further Info :

Pubmed ID

2948143

DOI: Digital Object Identifier

10.1016/0030-4220(86)90255-0

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Article Analysis
・Effects of etodolac
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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