Endocrine Treatment with 2 Years of Tamoxifen versus 2 Years of Exemestane in Postmenopausal Patients with High-Risk Early Breast Cancer and Persisting Circulating Tumor Cells - First Results of the SUCCESS C Endocrine Treatment Sub-Study.

Author: , Alunni-FabbroniMarianna, AndergassenUlrich, BeckmannMatthias W, FaschingPeter A, FehmTanja, FriedlThomas W P, GadeJörg, JanniWolfgang, LichteneggerWerner, LorenzRalf, MahnerSven, MüllerVolkmar, PantelKlaus, PolasikArkadius, RackBrigitte, RezaiMahdi, SchindlbeckChristian, SchneeweissAndreas, SchochterFabienne, SoelingUlrike, TeschHans, TrappElisabeth, TzschaschelMarie

Paper Details 
Original Abstract of the Article :
BACKGROUND: Optimal choice and sequence of endocrine treatment following adjuvant chemotherapy in postmenopausal early breast cancer patients are still under discussion and treatment stratification factors are missing. PATIENTS AND METHODS: Postmenopausal women with HER2-negative, hormone receptor-...See full text at original site
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引用元:
https://doi.org/10.1159/000485566

データ提供:米国国立医学図書館(NLM)

Tamoxifen vs. Exemestane: Choosing the Right Path Through the Breast Cancer Desert

My fellow researchers, let's navigate the complex terrain of [breast cancer], where the quest for optimal endocrine therapies continues. This research explores the effectiveness of two commonly used endocrine agents, tamoxifen and exemestane, in postmenopausal women with high-risk early breast cancer and persisting circulating tumor cells (CTCs). The authors investigate the efficacy of these agents in reducing CTCs, providing valuable insights for optimizing treatment strategies for this challenging disease. This research is like navigating a desert with two potential routes, each offering a unique path towards recovery.

Navigating the Crossroads of Endocrine Therapy

This research offers valuable insights into the effectiveness of tamoxifen and exemestane in reducing CTCs in postmenopausal women with high-risk early breast cancer. The authors demonstrate that both agents show comparable efficacy in clearing CTCs after two years of treatment. This study is like navigating a desert with two potential routes, each offering a unique path towards recovery. While both routes may lead to the same destination, the journey itself might be different. The research encourages further investigation to determine which path might be best for individual patients.

Choosing the Right Path for Your Journey

This research underscores the importance of individualized treatment approaches for breast cancer. The authors highlight the need for personalized care, recognizing that the optimal treatment strategy will vary depending on the specific needs and circumstances of each patient. This research encourages a comprehensive approach to treatment, taking into account the unique characteristics of each individual's journey. It's like finding a path through the desert that is tailored to each traveler's unique needs and abilities, ensuring their safe and successful passage.

Dr. Camel's Conclusion

This research offers a comparative analysis of tamoxifen and exemestane in the treatment of high-risk early breast cancer. The authors demonstrate that both agents show comparable efficacy in reducing circulating tumor cells, highlighting the importance of personalized care and the need for further research to determine the optimal treatment strategy for individual patients. It's like navigating a desert with two potential routes, each offering a unique path towards recovery. The journey itself might be different, but the destination remains the same: a future free from the burden of disease.

Date :
  1. Date Completed 2019-08-13
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

29490302

DOI: Digital Object Identifier

10.1159/000485566

Related Literature

SNS
PICO Info
in preparation
Languages

English

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