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Evaluating the effect of three newly approved overactive bladder syndrome treating agents on parotid and submandibular salivary glands: Modulation of CXCL10 expression.
Author: AboulhodaBasma Emad, AliEid Nassar
Original Abstract of the Article :
Despite enormous progresses in understanding pathophysiology of the lower urinary tract, antimuscarinics remain the chief clinically well-established approach for improving symptoms of overactive bladder (OAB). Dry mouth on the other hand remains one of the most untolerated systemic side effects of ...See full text at original site
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引用元:
https://doi.org/10.1016/j.acthis.2018.02.008
データ提供:米国国立医学図書館(NLM)
Overactive Bladder Syndrome: Evaluating the Impact of New Medications on Salivary Glands
Overactive bladder (OAB) is a common condition that can significantly impact quality of life. While antimuscarinics have been the mainstay treatment for OAB, their use is often hampered by the undesirable side effect of dry mouth. This study focuses on three newly approved drugs for OAB: trospium, darifenacin, and solifenacin. Researchers investigated the potential impact of these drugs on parotid and submandibular salivary glands, specifically exploring their effects on CXCL10 expression. This research provides valuable insights into the potential impact of these drugs on salivary gland function, contributing to a more comprehensive understanding of their safety and efficacy.
Navigating the Side Effects of OAB Medications
The study suggests that while these novel OAB medications offer hope for patients struggling with overactive bladder, it's crucial to be aware of their potential impact on salivary gland function. Understanding the potential side effects of these medications is essential for informed decision-making and personalized treatment plans. It's like traversing a vast desert - you need to be prepared for the challenges and have strategies to overcome them.
Finding the Right Balance in OAB Treatment
This research highlights the need for a balanced approach to OAB treatment, considering both the benefits and potential side effects of available medications. By weighing the advantages of these novel drugs against their potential impact on salivary gland function, clinicians can optimize treatment plans for individual patients. It's a delicate dance between balancing the need for relief from OAB symptoms with the need to mitigate potential side effects.
Dr.Camel's Conclusion
This study underscores the importance of considering the potential impact of OAB medications on salivary gland function. By carefully evaluating the benefits and risks of these new drugs, clinicians can ensure that patients receive the most appropriate and personalized treatment. It's a reminder that even in the realm of medical advancements, we must remain vigilant and strive for a balanced approach.
Date :
- Date Completed 2019-02-08
- Date Revised 2019-02-15
Further Info :
Related Literature
English
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