Administration of nasal nafarelin as compared with oral danazol for endometriosis. A multicenter double-blind comparative clinical trial.

Author: BerqvistC, ButtramV C, CorsonS L, HenzlM R, JacobsonJ, MoghissiK

Paper Details 
Original Abstract of the Article :
Treatment with nafarelin, a gonadotropin-releasing hormone agonist, reversibly inhibits ovarian function and induces hypoestrogenemia. To determine the efficacy of such hormonal manipulation in the treatment of endometriosis, we randomly assigned 213 patients with laparoscopically confirmed endometr...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM198802253180805

データ提供:米国国立医学図書館(NLM)

Endometriosis: Navigating Treatment Options

Endometriosis, a condition where uterine tissue grows outside the uterus, can be a painful and debilitating experience, like a thorny desert path. This study compares the effectiveness of two treatments for endometriosis: nasal nafarelin and oral danazol.

Nafarelin Shows Promise as a Treatment for Endometriosis

The researchers conducted a double-blind, randomized controlled trial, involving 213 patients with endometriosis. The results show that both nafarelin and danazol effectively reduced the severity of endometriosis, with similar rates of pregnancy success. However, nafarelin had fewer side effects, making it a more appealing option for many patients.

Finding the Right Path for You

Choosing the best treatment for endometriosis is like choosing the right path in the desert. This study highlights the importance of considering both the effectiveness and side effects of different treatment options. Consulting with a healthcare professional is crucial for determining the best course of action.

Dr.Camel's Conclusion

Endometriosis can be a challenging condition, but this study offers a clear comparison of two effective treatment options. Nafarelin emerges as a promising choice due to its effectiveness and favorable side effect profile. As a camel who has navigated the harsh realities of the desert, I understand the importance of finding the right path for individual needs. This study sheds light on the complexity of endometriosis and underscores the importance of personalized treatment plans.

Date :
  1. Date Completed 1988-03-15
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2963213

DOI: Digital Object Identifier

10.1056/NEJM198802253180805

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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