Paper Details 
Original Abstract of the Article :
Antihistamines are excreted into breast milk in small amounts; however, there are no adequate published studies or data concerning their effects on newborns and safety during breastfeeding. Thus, the development of sensitive and specific methodologies for the determination of antihistamines in breas...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/bmc.4260

データ提供:米国国立医学図書館(NLM)

Antihistamines in Breast Milk: A Sensitive and Specific GC-MS Method for Navigating the Desert of Maternal Medications

The field of [breastfeeding] is often like a vast, unforgiving desert, filled with challenges and uncertainties. Navigating the use of medications during breastfeeding requires a delicate balance. This study, a beacon in the [analytical chemistry] desert, presents a [fully validated method] for the [simultaneous determination of eleven antihistamines] in [breast milk] using [gas chromatography-mass spectrometry]. The authors, like skilled desert navigators, have developed a robust and precise method for [quantifying] these medications in [breast milk], providing valuable information for [pharmacokinetic and breastfeeding safety studies].

Uncovering the Secrets of Antihistamines in Breast Milk

The [limits of detection and quantification] achieved in this study, [1.50 and 5.00 ng/mL], are impressive, showcasing the sensitivity and specificity of the [GC-MS] method. The [linearity] and [accuracy] of the calibration curves further attest to the reliability of this technique. This method is a crucial tool for [investigating antihistamine-related clinical cases] and [evaluating the safety of antihistamines during breastfeeding].

Guiding Mothers Through the Desert of Medication Choices

This study provides valuable information for [healthcare professionals] and [mothers] navigating the complex landscape of [medication use during breastfeeding]. By providing a reliable and accurate method for [determining antihistamine concentrations in breast milk], this research paves the way for making informed decisions about the safety of these medications for both [mother] and [infant].

Dr.Camel's Conclusion

The authors' meticulous work provides a valuable tool for navigating the desert of [maternal medication use during breastfeeding]. By offering a sensitive and specific method for [antihistamine quantification], this study contributes to the safety and well-being of both [mother] and [infant]. This research is a testament to the power of [analytical chemistry] in addressing critical health challenges, offering a beacon of hope and clarity in a sometimes-uncertain landscape.

Date :
  1. Date Completed 2018-08-01
  2. Date Revised 2018-08-01
Further Info :

Pubmed ID

29644705

DOI: Digital Object Identifier

10.1002/bmc.4260

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.