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Longterm Safety and Efficacy of Subcutaneous Abatacept in Patients with Rheumatoid Arthritis: 5-year Results from a Phase IIIb Trial.
Author: AltenRieke, BanerjeeSubhashis, BoxJane, CovarrubiasArturo, DurezPatrick, ElegbeAyanbola, GenoveseMark C, KeisermanMauro, LegertonClarence W, LeonGustavo, LiXiaohui, MyslerEduardo, NashPeter, NasonovEvgeny, Pacheco-TenaCésar, Simon-CamposJ Abraham, ValenteRobert M, WongRobert
Original Abstract of the Article :
OBJECTIVE: To assess 5-year safety, tolerability, and efficacy of subcutaneous (SC) abatacept (ABA) in methotrexate (MTX)-refractory patients with rheumatoid arthritis (RA). METHODS: The Abatacept Comparison of sub[QU]cutaneous versus intravenous in Inadequate Responders to methotrexatE (ACQUIRE) p...See full text at original site
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引用元:
https://doi.org/10.3899/jrheum.170344
データ提供:米国国立医学図書館(NLM)
Long-Term Safety and Efficacy of Subcutaneous Abatacept in Patients with Rheumatoid Arthritis
The realm of rheumatology is vast and complex, like a desert stretching endlessly under the scorching sun. Researchers are always searching for effective and safe treatments for rheumatoid arthritis (RA). This particular study delves into the long-term safety and efficacy of subcutaneous (SC) abatacept (ABA) in patients with RA who haven't responded well to methotrexate (MTX). The study design involved a phase IIIb, randomized, double-dummy, multinational trial comparing SC and intravenous (IV) ABA. The researchers meticulously tracked the outcomes of patients receiving SC ABA over a 5-year period.
They found that SC ABA was well-tolerated and maintained its effectiveness over the long term. This is great news for patients with RA, as it offers them a viable treatment option with a consistent safety profile.
Long-Term Safety and Efficacy of Subcutaneous Abatacept
These 5-year results are significant because they provide strong evidence for the long-term safety and effectiveness of SC ABA. This is crucial for patients with RA, as it means they can potentially benefit from this treatment over an extended period without worrying about increased side effects.
Long-Term Treatment for Rheumatoid Arthritis
The findings suggest that SC ABA is a safe and effective long-term treatment for patients with RA who haven't responded well to MTX. It's important to remember that everyone's body is unique, like a snowflake in the desert. What works for one person may not work for another. Therefore, it's always crucial to discuss your treatment options with your doctor and find the approach that's best for your individual needs.
Dr. Camel's Conclusion
These findings provide valuable insights into the long-term treatment of RA. It's like finding a hidden oasis in the desert, offering hope for those who have been struggling with this chronic condition.
Date :
- Date Completed 2019-11-11
- Date Revised 2019-11-11
Further Info :
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