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Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial.

Author: FukuchiTakehide, HirasawaKingo, IkedaRyosuke, IrieKuniyasu, IshiiYasuaki, KanekoHiroaki, KobayashiRyosuke, KondoMasaaki, MaedaShin, MakazuMakomo, SasakiTomohiko, SatoChiko, SatoTakeshi, ShibataWataru, SueSoichiro, TamuraToshihide, YamadaHiroaki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Vonoprazan and esomeprazole showed no significant difference in the healing of artificial ulcers after endoscopic submucosal dissection (ESD). Both drugs effectively healed artificial ulcers after ESD.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Vonoprazan affords more clinical benefits than proton pump inhibitors (PPIs) during the healing of gastroduodenal ulcers. However, it remains controversial whether vonoprazan is more effective than PPIs when used to heal artificial ulcers arising after endoscopic submucosal dissection (E...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835268/

データ提供：米国国立医学図書館（NLM）

Vonoprazan vs. Esomeprazole: A New Oasis in the Desert of Ulcer Healing

Gastroduodenal ulcers, like wounds in the desert, can be slow to heal and prone to complications. This study compares the effectiveness of vonoprazan, a new drug, to esomeprazole, a common proton pump inhibitor (PPI), in promoting the healing of artificial ulcers created during endoscopic submucosal dissection (ESD). The researchers found that both vonoprazan and esomeprazole were effective in promoting ulcer healing, suggesting that vonoprazan may offer a viable alternative to PPIs in this context.

A New Path to Ulcer Healing

This study suggests that vonoprazan, a new drug, may offer a comparable alternative to PPIs for promoting the healing of artificial ulcers after ESD.

Navigating the Challenges of Ulcer Healing

If you're facing the challenges of gastroduodenal ulcers, it's crucial to consult with a medical professional to develop a personalized treatment plan that addresses your individual needs and promotes optimal healing.

Dr.Camel's Conclusion

This study provides evidence that vonoprazan may be an effective alternative to PPIs for promoting the healing of artificial ulcers after ESD. However, further research is needed to fully understand its long-term benefits and confirm its safety and efficacy in a wider range of patients.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

29670650

DOI: Digital Object Identifier

PMC5835268

Related Literature

Article Analysis
・Effects of vonoprazan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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