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Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.
Author: BurgerMelanie, FreissmuthMichael, HamaliBulut, HolyMarion, JaentschKathrin, KudlacekOliver, MolinMartina, PichlerSandra, SchickerKlaus, SehrEva Maria, WischnitzkiElisabeth
Original Abstract of the Article :
The parasitic liver fluke Fasciola hepatica infests mainly ruminants, but it can also cause fasciolosis in people, who ingest the metacercariae encysted on plants. The drug of choice to treat fasciolosis is triclabendazole (TBZ), which has been on the market for several decades. This is also true fo...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942844/
データ提供:米国国立医学図書館(NLM)
Uncovering a New Drug Target for Liver Fluke
Imagine a camel navigating a vast desert, encountering a hidden oasis teeming with life. This study dives into the complex world of the liver fluke Fasciola hepatica, a parasitic worm that infects ruminants and humans. The researchers, like intrepid explorers charting an uncharted territory, discovered a new drug target: the sodium- and chloride-dependent taurine transporter that plays a critical role in the fluke's survival.
A New Target for Combating Liver Fluke
The study's findings suggest that the taurine transporter is essential for the liver fluke's survival in the harsh environment of the bile duct. This discovery, like finding a hidden spring in the desert, provides a new target for developing drugs to combat this parasitic infection.
Fighting Parasites and Protecting Health
This study underscores the importance of research in parasitology and the need to identify new drug targets to combat parasitic infections. It highlights the potential for innovative approaches to address global health challenges and protect individuals from the harmful effects of parasites.
Dr. Camel's Conclusion
This study sheds light on the crucial role of the taurine transporter in the survival of liver flukes. This research provides a promising new target for drug development and opens up exciting possibilities for combating this parasitic infection.
Date :
- Date Completed 2018-06-18
- Date Revised 2018-12-02
Further Info :
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