Alternatives to Biologics in Management of Knee Osteoarthritis: A Systematic Review.

Author: HassanFadi, MaffulliNicola, MurrellWilliam D, RefaloAndrew

Paper Details 
Original Abstract of the Article :
BACKGROUND: Knee osteoarthritis (KOA) is a common condition encountered by physicians. KOA is addressed by a wide array of modalities including a number of nonbiological treatments. METHODS: PubMed, ISI Web of Science, and SPORTDiscus were searched for level 1 to 4 studies published from inception ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/29722769

データ提供:米国国立医学図書館(NLM)

Knee Osteoarthritis: Seeking Alternatives in the Desert

Knee osteoarthritis (KOA), a condition that affects millions, is like a desert landscape – sometimes harsh and difficult to navigate. This study explores alternative non-biological treatments for KOA, offering hope for patients seeking effective management options. Like a camel seeking a refreshing oasis, researchers examined a range of treatments, seeking the most effective solutions to alleviate pain and improve function.

Navigating the Desert: Finding Effective Alternatives

The research, like a skilled explorer, found moderate evidence supporting prolotherapy as a potential treatment for KOA. It also identified limited evidence for the effectiveness of botulinum toxin type A, sodium bicarbonate and calcium gluconate, and low-molecular weight fraction of 5% human serum albumin. These findings provide promising leads, but more research is needed to fully understand the effectiveness of these alternative therapies.

Finding Relief: A Camel's Perspective

Navigating the desert of KOA can be challenging, but this study offers promising alternatives. While more research is needed, these findings suggest that patients may find relief with treatments like prolotherapy, botulinum toxin type A, and other non-biological approaches. It's crucial to consult with a doctor to determine the best treatment plan based on individual needs and medical history.

Dr.Camel's Conclusion

This study provides a valuable roadmap for managing KOA, highlighting the potential benefits of various non-biological treatments. Like a camel seeking a safe path in the desert, patients with KOA can find relief and improved quality of life by considering these alternative options. More research is needed to fully understand the efficacy and safety of these treatments, but this study offers a promising start.

Date :
  1. Date Completed 2018-10-10
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

29722769

DOI: Digital Object Identifier

00132585-201806000-00009

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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