An expert consensus to standardise definitions, diagnosis and treatment targets for anti-fibrotic stricture therapies in Crohn's disease.

Author: BakerM E, BettenworthD, BouhnikY, Di SabatinoA, DignassA, FeaganB G, FletcherJ G, JairathV, MaC, NelsonS A, PanesJ, ParkerC E, RiederF, RimolaJ, RoglerG, SandbornW J, StidhamR W, StokerJ, TaylorS A, WilliamsonL A, van AsscheG

Paper Details 
Original Abstract of the Article :
Fibrotic stricture is a common complication of Crohn's disease (CD) affecting approximately half of all patients. No specific anti-fibrotic therapies are available; however, several therapies are currently under evaluation. Drug development for the indication of stricturing CD is hampered by a lack ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/29920726

データ提供:米国国立医学図書館(NLM)

Standardizing Definitions and Treatment Targets for Crohn's Disease

Crohn's disease, a debilitating inflammatory bowel disorder, can lead to fibrotic strictures, impacting the quality of life for many patients. This study addresses the critical need for standardized definitions, diagnostic modalities, and treatment targets for patients with stricturing Crohn's disease. The researchers highlight the challenges faced in drug development for this indication, emphasizing the lack of consensus in defining, diagnosing, and managing this specific aspect of Crohn's disease.

The Importance of Standardized Approaches for Crohn's Disease Treatment

The study emphasizes the critical need for standardized approaches to defining, diagnosing, and managing fibrotic strictures in Crohn's disease. The researchers call for a collaborative effort to establish clear criteria for clinical trial eligibility, endpoints, and treatment targets, paving the way for more effective and targeted drug development for this challenging condition.

Moving Towards More Effective Crohn's Disease Treatment

This research underscores the importance of a unified approach to improving the care of patients with stricturing Crohn's disease. The researchers highlight the need for further research and collaboration to develop standardized methodologies and treatment strategies, leading to more effective and personalized approaches to managing this debilitating condition.

Dr. Camel's Conclusion

This research, like a camel caravan embarking on a journey through the desert, highlights the importance of a unified approach to managing Crohn's disease. The study emphasizes the need for clear definitions, standardized methodologies, and collaborative efforts to ensure the best possible outcomes for patients living with this chronic condition. Remember, just as a caravan relies on a shared purpose and direction to succeed, advancing the treatment of Crohn's disease requires a collaborative effort and a unified vision.

Date :
  1. Date Completed 2019-08-14
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

29920726

DOI: Digital Object Identifier

NIHMS971906

SNS
PICO Info
in preparation
Languages

English

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