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An expert consensus to standardise definitions, diagnosis and treatment targets for anti-fibrotic stricture therapies in Crohn's disease.
Author: BakerM E, BettenworthD, BouhnikY, Di SabatinoA, DignassA, FeaganB G, FletcherJ G, JairathV, MaC, NelsonS A, PanesJ, ParkerC E, RiederF, RimolaJ, RoglerG, SandbornW J, StidhamR W, StokerJ, TaylorS A, WilliamsonL A, van AsscheG
Original Abstract of the Article :
Fibrotic stricture is a common complication of Crohn's disease (CD) affecting approximately half of all patients. No specific anti-fibrotic therapies are available; however, several therapies are currently under evaluation. Drug development for the indication of stricturing CD is hampered by a lack ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/29920726
データ提供:米国国立医学図書館(NLM)
Standardizing Definitions and Treatment Targets for Crohn's Disease
Crohn's disease, a debilitating inflammatory bowel disorder, can lead to fibrotic strictures, impacting the quality of life for many patients. This study addresses the critical need for standardized definitions, diagnostic modalities, and treatment targets for patients with stricturing Crohn's disease. The researchers highlight the challenges faced in drug development for this indication, emphasizing the lack of consensus in defining, diagnosing, and managing this specific aspect of Crohn's disease.
The Importance of Standardized Approaches for Crohn's Disease Treatment
The study emphasizes the critical need for standardized approaches to defining, diagnosing, and managing fibrotic strictures in Crohn's disease. The researchers call for a collaborative effort to establish clear criteria for clinical trial eligibility, endpoints, and treatment targets, paving the way for more effective and targeted drug development for this challenging condition.
Moving Towards More Effective Crohn's Disease Treatment
This research underscores the importance of a unified approach to improving the care of patients with stricturing Crohn's disease. The researchers highlight the need for further research and collaboration to develop standardized methodologies and treatment strategies, leading to more effective and personalized approaches to managing this debilitating condition.
Dr. Camel's Conclusion
This research, like a camel caravan embarking on a journey through the desert, highlights the importance of a unified approach to managing Crohn's disease. The study emphasizes the need for clear definitions, standardized methodologies, and collaborative efforts to ensure the best possible outcomes for patients living with this chronic condition. Remember, just as a caravan relies on a shared purpose and direction to succeed, advancing the treatment of Crohn's disease requires a collaborative effort and a unified vision.
Date :
- Date Completed 2019-08-14
- Date Revised 2019-08-14
Further Info :
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