Bempedoic Acid (ETC-1002): ATP Citrate Lyase Inhibitor: Review of a First-in-Class Medication with Potential Benefit in Statin-Refractory Cases.

Author: FrishmanWilliam H, NaborsChristopher, YandrapalliSrikanth, ZagelbaumNicole K

Paper Details 
Original Abstract of the Article :
Bempedoic acid (BA; ETC-1002) is a new agent that reduces cholesterol synthesis through inhibition of adenosine triphosphate citrate lyase, an enzyme upstream from 3-hydroxy-3-methylglutaryl-coenzyme A. In animal models, BA also influences fatty acid synthesis, but in humans, its role is limited pri...See full text at original site
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引用元:
https://doi.org/10.1097/CRD.0000000000000218

データ提供:米国国立医学図書館(NLM)

Bempedoic Acid: A New Hope in the Desert of High Cholesterol

High cholesterol, a silent threat lurking in the shadows of our bodies, is a significant risk factor for heart disease. This study explores the potential of a new cholesterol-lowering medication, bempedoic acid, to combat this silent adversary. Using [research methods], the research team delved into the efficacy, safety, and potential benefits of bempedoic acid. The results of their investigation suggest that bempedoic acid could offer a refreshing oasis in the desert of high cholesterol.

A New Dawn in the Desert: Bempedoic Acid Shows Promise in Cholesterol Management

The study paints a promising picture of bempedoic acid's potential to lower cholesterol levels. The researchers found that bempedoic acid effectively reduced LDL-C, a key player in the development of heart disease, both alone and in combination with other cholesterol-lowering medications. This suggests that bempedoic acid could be a valuable tool in the fight against high cholesterol, potentially offering a new path towards a healthier heart.

A New Oasis of Hope: Bempedoic Acid's Potential Benefits

The study's findings hold great promise for individuals seeking to manage their cholesterol levels and reduce their risk of heart disease. The research suggests that bempedoic acid could provide a valuable alternative for those who cannot tolerate or benefit from statins, offering a new oasis of hope in the desert of high cholesterol. The study's findings warrant further investigation and exploration of bempedoic acid's potential as a safe and effective treatment option for high cholesterol.

Dr. Camel's Conclusion

This study sheds light on the potential of bempedoic acid as a new and effective treatment for high cholesterol. The research highlights bempedoic acid's ability to effectively lower LDL-C, a key risk factor for heart disease. The study's findings offer hope for individuals seeking to manage their cholesterol levels and reduce their risk of heart disease. This research is a valuable step forward in the ongoing battle against high cholesterol.

Date :
  1. Date Completed 2019-03-13
  2. Date Revised 2019-03-13
Further Info :

Pubmed ID

29939848

DOI: Digital Object Identifier

10.1097/CRD.0000000000000218

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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