Do bismuth complexes hold promise as antileishmanial drugs?

Author: AndrewsPhilip C, KedzierskiLukasz, OngYih Ching

Paper Details 
Original Abstract of the Article :
Even after 70 years, pentavalent antimonials sodium stibogluconate and meglumine antimoniate remain the most important and cost-effective antileishmanial drugs. However, the drugs cannot be delivered orally and treatment involves intravascular or intramuscular injections for 28 days under strict med...See full text at original site
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引用元:
https://doi.org/10.4155/fmc-2017-0287

データ提供:米国国立医学図書館(NLM)

Bismuth: A Potential Oasis in the Fight Against Leishmaniasis

Leishmaniasis is a parasitic disease spread by sandflies that can cause severe health problems. Current treatments, like pentavalent antimonials, are often challenging due to their toxicity and need for injections. This study explores the potential of bismuth, a metal element found in the same group as antimony, as a safer alternative for treating Leishmaniasis. The researchers reviewed recent studies on bismuth-based compounds and found promising results. While bismuth has long been recognized for its antimicrobial properties, its potential as an antileishmanial agent is a relatively new area of research. The researchers highlight the potential of bismuth to offer similar efficacy to antimony while potentially being less toxic and possibly offering the benefit of oral administration. This opens up exciting possibilities for developing safer and more convenient treatments for Leishmaniasis.

Emerging from the Sands: A New Hope for Leishmaniasis Treatment

The research on bismuth-based compounds for treating Leishmaniasis is encouraging. If bismuth proves to be a viable alternative to current treatments, it could have a significant impact on the lives of countless individuals affected by this debilitating disease. The potential for oral administration would also be a major breakthrough, making treatment more accessible and convenient.

A Beacon of Hope: Living with Leishmaniasis

Leishmaniasis can be a serious and challenging condition, but there is reason for hope. The research on bismuth-based compounds offers a promising avenue for new and improved treatments. If you're concerned about Leishmaniasis, talk to your doctor about the latest developments and available treatment options.

Dr.Camel's Conclusion

This study suggests a promising new direction in the fight against Leishmaniasis. Bismuth holds potential as a safer and potentially orally-administered treatment option. As research progresses, we may find a new oasis in the desert of this debilitating disease.

Date :
  1. Date Completed 2019-05-20
  2. Date Revised 2019-05-20
Further Info :

Pubmed ID

29961352

DOI: Digital Object Identifier

10.4155/fmc-2017-0287

Related Literature

SNS
PICO Info
in preparation
Languages

English

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