Sulbactam/ampicillin compared with cefoxitin for chemoprophylaxis in elective colorectal surgery.

Author: KarranS J, de la HuntM N

Paper Details 
Original Abstract of the Article :
In a prospective, randomized, comparative study, patients undergoing elective major colorectal surgery received four six-hour doses of either sulbactam (a beta-lactamase inhibitor) with ampicillin (1 gm with 1 gm), or cefoxitin (2 gm) commencing at induction of anesthesia. The groups were well match...See full text at original site
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引用元:
https://doi.org/10.1007/BF02555011

データ提供:米国国立医学図書館(NLM)

Sulbactam/Ampicillin vs. Cefoxitin for Colorectal Surgery Prophylaxis

This study, like a careful traveler navigating a desert landscape, compares two different routes for [chemoprophylaxis] in [elective colorectal surgery]. Researchers used [a prospective, randomized, comparative study] to assess the effectiveness of [sulbactam/ampicillin] compared to [cefoxitin]. The results of this journey reveal important insights into the best approach for preventing infections.

The study's [well-matched groups] provide a reliable framework for comparison, much like using a compass to ensure an accurate course. The authors observed [similar rates of wound sepsis, deep sepsis, and anastomotic leaks] between the two treatment groups, suggesting that both approaches are effective in preventing serious infections.

Sulbactam/Ampicillin: A Safe and Effective Alternative

The study concludes that [sulbactam/ampicillin] provides a [safe and effective alternative] to [cefoxitin]. This finding, like a newly discovered oasis, offers a viable option for patients undergoing [elective colorectal surgery], allowing them to navigate their recovery with greater confidence.

Choosing the Right Prophylaxis

This study highlights the importance of carefully considering [chemoprophylaxis] options for patients undergoing surgery. Choosing the right approach can make a significant difference in their recovery journey, like selecting the optimal path through a vast desert.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness of different [chemoprophylaxis] options for [elective colorectal surgery]. The findings suggest that [sulbactam/ampicillin] offers a safe and effective alternative to [cefoxitin], offering patients a choice based on their individual needs and preferences. It's a reminder that even in the challenging terrain of surgery, there are often multiple paths to a successful outcome.

Date :
  1. Date Completed 1986-03-24
  2. Date Revised 2019-07-21
Further Info :

Pubmed ID

3002735

DOI: Digital Object Identifier

10.1007/BF02555011

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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