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Perspectives on preoperative systemic treatment and breast conservative surgery: One step forward or two steps back?

Author: CardosoF, CortesJ, CuriglianoG, KovacsT, PoortmansP, RubioI T, WyldL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Giving chemotherapy before surgery (preoperative systemic therapy, PST) is becoming a standard approach for both early and advanced breast cancer. Studies have shown that PST is as effective as chemotherapy after surgery in terms of overall survival. PST also allows more women to have breast-conserving surgery and increases the chance of a complete response to treatment. While early studies suggested a higher risk of cancer returning in the same area, optimizing treatment and working with a team of specialists is key to achieving the best outcomes.
Paper Details　
Original Abstract of the Article :
Preoperative systemic therapy (PST) has become an accepted treatment not only for locally advanced but also for early stage breast cancer patients. Clinical trials have demonstrated that the use of PST is equally to adjuvant treatments in terms of overall survival, and has the advantage of increasin...See full text at original site
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引用元：
https://doi.org/10.1016/j.breast.2018.07.008

データ提供：米国国立医学図書館（NLM）

Preoperative Systemic Therapy for Breast Cancer: A New Oasis in the Desert of Treatment Strategies

Breast cancer treatment has evolved significantly, with preoperative systemic therapy (PST) becoming increasingly common, even for early-stage patients. This study explores the potential benefits and challenges of using PST before breast-conserving surgery. The authors delve into the research, examining how PST can increase breast-conserving surgery rates and achieve pathologic complete response, a crucial indicator of treatment success. They also acknowledge the potential risks associated with this approach, highlighting the need for a multidisciplinary approach to ensure optimal outcomes.

PST: A Promising Approach in the Desert of Breast Cancer Treatment

This study provides valuable insights into the use of PST for breast cancer. The authors highlight the potential benefits of this approach, including increased rates of breast-conserving surgery and pathologic complete response, while acknowledging the need for further research to address potential concerns. This research underscores the need for a multidisciplinary approach to breast cancer treatment, ensuring that each patient receives the most effective and individualized care.

Navigating the Desert of Breast Cancer Care

This research emphasizes the importance of ongoing research and innovation in breast cancer treatment. The findings suggest that PST offers a promising avenue for achieving optimal outcomes, but a multidisciplinary approach is crucial for addressing potential risks and ensuring patient safety. This research provides valuable insights for navigating the desert of breast cancer care, seeking the most effective and compassionate treatment strategies.

Dr.Camel's Conclusion

The desert of breast cancer treatment is constantly evolving, and this research sheds light on the potential benefits and challenges of using PST. This approach shows promise for achieving optimal outcomes, but it's crucial to recognize that every patient is different and requires individualized care. The research highlights the importance of a multidisciplinary approach, ensuring that each patient receives the most effective and compassionate treatment possible.

Date :
  1. Date Completed 2019-01-11
  2. Date Revised 2019-01-11
Further Info :

Pubmed ID

30056250

DOI: Digital Object Identifier

10.1016/j.breast.2018.07.008

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・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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