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Long-Term Effects of Iloperidone on Cerebral Serotonin and Adrenoceptor Subtypes.
Author: ChoiYong Kee, TaraziFrank I
Original Abstract of the Article :
The atypical antipsychotic drug iloperidone has high affinity for a wide range of neurotransmitter receptors, including serotonin and adrenoceptors. We examined the long-term effects of multiple doses of iloperidone (0.5, 1.5, or 5 mg/kg) on serotonin (5-HT) 5-HT<sub>1A</sub>, 5-HT<sub>2A</sub>...See full text at original site
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引用元:
https://doi.org/10.1007/s12031-018-1133-z
データ提供:米国国立医学図書館(NLM)
Iloperidone: A Long-Term Journey Through the Desert of Schizophrenia
Schizophrenia is a complex and challenging mental health condition, often leaving individuals feeling lost in a desert of symptoms. This study focuses on iloperidone, an atypical antipsychotic drug, and its long-term effects on neurotransmitter receptors in the brain. The researchers examined the impact of iloperidone on serotonin and adrenoceptor subtypes in various brain regions, investigating its potential to manage the symptoms of schizophrenia over time.
Iloperidone: A Potential Oasis in the Desert of Schizophrenia
The study revealed that iloperidone had region- and dose-specific effects on serotonin and adrenoceptors in the brain. Long-term treatment with iloperidone led to significant increases in serotonin 5-HT1A receptors and decreases in serotonin 5-HT2A receptors in several brain regions. These findings suggest that iloperidone may play a role in managing both positive and negative symptoms of schizophrenia by influencing the activity of key neurotransmitter systems. Just as a traveler finds solace in a cool oasis, iloperidone may offer a potential path to relief for individuals struggling with schizophrenia.
Navigating the Desert of Schizophrenia: The Role of Iloperidone
The study's findings provide a glimpse into the complex interplay of neurotransmitter systems in schizophrenia. Iloperidone's effects on serotonin and adrenoceptor subtypes suggest that it may offer a valuable tool for managing symptoms, but it's essential to remember that schizophrenia is a multifaceted condition, and treatment approaches should be tailored to individual needs. Consult with a qualified healthcare professional to discuss your options and create a personalized plan that addresses your specific challenges. Just as a desert traveler relies on a trusted guide, working with a mental health professional can provide support and guidance in navigating the desert of schizophrenia.
Dr. Camel's Conclusion
Iloperidone shows potential in managing schizophrenia by influencing neurotransmitter receptor activity. However, individual treatment plans are crucial for effectively addressing this complex condition.
Date :
- Date Completed 2018-11-09
- Date Revised 2020-02-25
Further Info :
Related Literature
English
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