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Acute Liver Injury Induced by Sitagliptin: Report of Two Cases and Review of Literature.
Author: AzizKashif, SachmechiIssac, ShahbazAmir, SharifzadehMohaddeseh, UmairMuhammad
Original Abstract of the Article :
We present two cases of acute liver injury associated with sitagliptin. The first case was a 58-year-old male with a history of poorly controlled type 2 diabetes mellitus and hyperlipidemia. Sitagliptin was added for better control of diabetes. After initiation of sitagliptin, the patient's serum al...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089488/
データ提供:米国国立医学図書館(NLM)
Sitagliptin: A Potential Cause of Acute Liver Injury
The [use of medications for type 2 diabetes] is widespread, with researchers constantly monitoring their [safety and efficacy]. This study reports [two cases of acute liver injury] associated with [sitagliptin], a [dipeptidyl peptidase 4 (DPP-4) inhibitor] medication. The researchers describe the [clinical presentation and laboratory findings] of these two patients, both of whom experienced [elevated liver enzyme levels] after starting sitagliptin therapy. This research raises concerns about the [potential for liver injury] associated with sitagliptin and highlights the need for [further research] to understand this phenomenon.
Sitagliptin: A Potential Risk Factor for Liver Injury
This case report suggests that [sitagliptin may be a potential cause of acute liver injury] in some individuals. While [most patients tolerate sitagliptin well], these cases underscore the [importance of monitoring liver function] in patients taking this medication.
Understanding Medication Safety: A Continuous Journey
This research is like a vigilant camel caravan, carefully monitoring the desert landscape for potential hazards. By staying informed about the [potential side effects of medications], we can ensure the safety and well-being of patients.
Dr. Camel's Conclusion
This case report serves as a reminder that even medications with a generally good safety profile can have unexpected side effects. It's crucial to be aware of these potential risks and to work closely with healthcare providers to ensure the safety and well-being of patients taking medications for type 2 diabetes.
Date :
- Date Completed n.d.
- Date Revised 2020-09-30
Further Info :
Related Literature
English
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