Acute Liver Injury Induced by Sitagliptin: Report of Two Cases and Review of Literature.

Author: AzizKashif, SachmechiIssac, ShahbazAmir, SharifzadehMohaddeseh, UmairMuhammad

Paper Details 
Original Abstract of the Article :
We present two cases of acute liver injury associated with sitagliptin. The first case was a 58-year-old male with a history of poorly controlled type 2 diabetes mellitus and hyperlipidemia. Sitagliptin was added for better control of diabetes. After initiation of sitagliptin, the patient's serum al...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089488/

データ提供:米国国立医学図書館(NLM)

Sitagliptin: A Potential Cause of Acute Liver Injury

The [use of medications for type 2 diabetes] is widespread, with researchers constantly monitoring their [safety and efficacy]. This study reports [two cases of acute liver injury] associated with [sitagliptin], a [dipeptidyl peptidase 4 (DPP-4) inhibitor] medication. The researchers describe the [clinical presentation and laboratory findings] of these two patients, both of whom experienced [elevated liver enzyme levels] after starting sitagliptin therapy. This research raises concerns about the [potential for liver injury] associated with sitagliptin and highlights the need for [further research] to understand this phenomenon.

Sitagliptin: A Potential Risk Factor for Liver Injury

This case report suggests that [sitagliptin may be a potential cause of acute liver injury] in some individuals. While [most patients tolerate sitagliptin well], these cases underscore the [importance of monitoring liver function] in patients taking this medication.

Understanding Medication Safety: A Continuous Journey

This research is like a vigilant camel caravan, carefully monitoring the desert landscape for potential hazards. By staying informed about the [potential side effects of medications], we can ensure the safety and well-being of patients.

Dr. Camel's Conclusion

This case report serves as a reminder that even medications with a generally good safety profile can have unexpected side effects. It's crucial to be aware of these potential risks and to work closely with healthcare providers to ensure the safety and well-being of patients taking medications for type 2 diabetes.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

30112252

DOI: Digital Object Identifier

PMC6089488

Related Literature

SNS
PICO Info
in preparation
Languages

English

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