Indole and 2,4-Thiazolidinedione conjugates as potential anticancer modulators.

Author: AlcaroStefano, AmatoRosario, BrunettiAntonio, ColicaCarmela, CoriglianoDomenica M, De SarroGiovambattista, DubeyPramod K, IndrasenaAdisherla, LupiaAntonio, MessineoSebastiano, PatelRahul, ReddyChittireddy Venkata Ramana, SyedRiyaz

Paper Details 
Original Abstract of the Article :
Thiazolidinediones (TZDs), also called glitazones, are five-membered carbon ring molecules commonly used for the management of insulin resistance and type 2 diabetes. Recently, many prospective studies have also documented the impact of these compounds as anti-proliferative agents, though several ne...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087425/

データ提供:米国国立医学図書館(NLM)

Indole and 2,4-Thiazolidinedione Conjugates: A New Frontier in Anticancer Therapy

The search for effective and safe anticancer therapies continues to be a primary focus of medical research. This study explores the potential of indole and 2,4-thiazolidinedione (TZD) conjugates as novel anticancer modulators. The researchers synthesized a series of TZD analogues, aiming to improve the anticancer properties of these compounds while minimizing their known side effects, such as hepatotoxicity and water retention. The study's findings offer promising insights into the potential of these novel conjugates as anticancer agents.

New Hope for Anticancer Therapy

The study's findings suggest that indole and TZD conjugates may offer a promising new approach to anticancer therapy. The researchers demonstrated the anticancer activity of these novel conjugates, highlighting their potential to target and inhibit cancer cell growth. The study's findings provide a foundation for further research into the efficacy, safety, and mechanisms of action of these compounds, potentially paving the way for the development of novel and effective anticancer drugs.

A Desert of Hope: The Search for Anticancer Therapies

Imagine a vast desert, where the sands of time hold countless secrets and potential remedies. Cancer, like a relentless sandstorm, can wreak havoc on the body. This research, like a persistent desert explorer, searches for new and effective weapons to combat this devastating disease. The study's findings offer a glimmer of hope, highlighting the potential of indole and TZD conjugates to provide a safe and effective treatment for cancer patients.

Dr.Camel's Conclusion

The search for effective anticancer therapies is a continuous journey through the desert of medical research. This study, like a beacon of hope in the midst of the sands, highlights the potential of indole and TZD conjugates as novel anticancer agents. The study's findings are a testament to the enduring pursuit of knowledge and innovation in the fight against cancer, offering a promising glimpse into the future of anticancer therapy.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

30123711

DOI: Digital Object Identifier

PMC6087425

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.