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Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-analysis.

Author: BlackChristopher J, BurrNicholas E, FordAlexander C, HoughtonLesley A, MoayyediPaul, QuigleyEamonn M M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This network meta-analysis compares the efficacy of various secretagogues approved for irritable bowel syndrome with constipation (IBS-C). The relative efficacy of these drugs is unclear due to the lack of head-to-head randomized controlled trials.
Paper Details　
Original Abstract of the Article :
Several secretagogues have been approved for the treatment of irritable bowel syndrome with constipation (IBS-C). However, their relative efficacy is unclear because there have been no head-to-head randomized controlled trials. We conducted a network meta-analysis to compare their efficacies in pati...See full text at original site
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引用元：
https://doi.org/10.1053/j.gastro.2018.08.021

データ提供：米国国立医学図書館（NLM）

Irritable Bowel Syndrome with Constipation: Seeking Relief in the Desert of Gut Health

Irritable bowel syndrome with constipation (IBS-C) is like a stubborn sandstorm in the desert of our digestive system, causing discomfort and disruption. This study examines the relative efficacy of various secretagogues, medications that stimulate bowel movements, in treating IBS-C.

Finding the Right Oasis: A Comparative Analysis of Secretagogues

Using a network meta-analysis, the study compares the effectiveness of different secretagogues, offering insights into their relative strengths and weaknesses. It's like exploring different oases in the desert, seeking the one that best suits our individual needs. The study highlights the importance of carefully considering the individual patient's needs and characteristics when selecting the most appropriate treatment.

Navigating the Desert of IBS-C: A Guide for Patients

This research provides valuable information for individuals seeking relief from IBS-C. It's like having a skilled camel guide who can help you navigate the complex terrain of digestive disorders. The study encourages patients to discuss their treatment options with their healthcare providers to find the most effective and personalized approach to managing their symptoms.

Dr. Camel's Conclusion

This research provides valuable insights into the effectiveness of various secretagogues for treating IBS-C. By comparing the efficacy of different medications, the study offers a roadmap for healthcare providers and patients in choosing the most appropriate treatment. It's a reminder that the desert of digestive health is a complex and individualistic landscape, and finding the right oasis of treatment is crucial to achieving lasting relief.

Date :
  1. Date Completed 2019-01-07
  2. Date Revised 2021-04-18
Further Info :

Pubmed ID

30144426

DOI: Digital Object Identifier

10.1053/j.gastro.2018.08.021

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