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Pharmacokinetic and pharmacodynamic studies of etodolac loaded vesicular gels on rats by transdermal delivery.
Author: MadhaviNimmathota, SudhakarBeeravelli, Suresh ReddyK V N, Vijaya RatnaJayanthi
Original Abstract of the Article :
BACKGROUND: The present study includes the development of liposomal and ethosomal gels for transdermal delivery to overcome the side effects associated with oral route. METHODS: The liposomes and ethosomes were prepared by 3 RESULTS: The pharmacokinetic study reveals that the half life of etodolac...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154486/
データ提供：米国国立医学図書館（NLM）
Etodolac: A New Oasis in the Desert of Transdermal Delivery
The development of effective and safe drug delivery systems is a constant endeavor in the field of pharmacy. This research explores the potential of vesicular gels, specifically liposomes and ethosomes, for transdermal delivery of etodolac, a nonsteroidal anti-inflammatory drug (NSAID). The authors conduct pharmacokinetic and pharmacodynamic studies in rats, comparing the efficacy of vesicular gels to a commercially available formulation. This study highlights the potential advantages of vesicular gels in enhancing drug delivery and reducing side effects associated with oral administration.
Vesicular Gels: A Promising Approach to Transdermal Delivery
This research explores the potential of vesicular gels, specifically liposomes and ethosomes, for transdermal delivery of etodolac, a nonsteroidal anti-inflammatory drug (NSAID). The authors conduct pharmacokinetic and pharmacodynamic studies in rats, demonstrating the superior efficacy of vesicular gels compared to a commercially available formulation. This study highlights the potential of vesicular gels as a promising drug delivery system, offering advantages in terms of efficacy, safety, and patient convenience.
Navigating the Sands of Drug Delivery: A Guide for Researchers
This research provides valuable insights into the potential of vesicular gels as a promising drug delivery system. The authors demonstrate the superior efficacy of vesicular gels compared to a commercially available formulation, highlighting the potential for improved drug delivery and reduced side effects. This information encourages further research and development in the field of transdermal drug delivery, potentially leading to more effective and patient-friendly treatment options.
Dr. Camel's Conclusion
This research explores the potential of vesicular gels, specifically liposomes and ethosomes, for transdermal delivery of etodolac, demonstrating their superior efficacy compared to a commercially available formulation. This study highlights the potential of vesicular gels as a promising drug delivery system, offering advantages in terms of efficacy, safety, and patient convenience.
Date :
- Date Completed n.d.
- Date Revised 2019-11-20
Further Info :
Related Literature
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