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Comparison between montelukast and tiotropium as add-on therapy to inhaled corticosteroids plus a long-acting β<sub>2</sub>-agonist in for patients with asthma.
Author: AkitsuKenta, HoshinoMakoto, OhtawaJunichi
Original Abstract of the Article :
<i>Objective</i>: Asthma often remains uncontrolled despite treatment with inhaled corticosteroids (ICS) alone or with ICS plus a long-acting β<sub>2</sub>-agonist (LABA). The recommended alternative is the addition of either montelukast or tiotropium. The aim of this study was to compare the ...See full text at original site
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引用元：
https://doi.org/10.1080/02770903.2018.1514047
データ提供：米国国立医学図書館（NLM）
Asthma: Finding the Right Path to Control
The realm of asthma is a challenging landscape, with patients often seeking effective treatments to manage their symptoms and improve their quality of life. This study explores the effectiveness of two add-on therapies, montelukast and tiotropium, in patients with asthma who remain uncontrolled despite standard treatments.
A Diverging Path: Montelukast vs. Tiotropium
The researchers compared the effects of montelukast and tiotropium as add-on therapies for patients with asthma who were already receiving inhaled corticosteroids (ICS) plus a long-acting beta2-agonist (LABA). It's like two caravans embarking on separate journeys through the desert, each following a different path to reach their destination. The study found that montelukast was more effective in reducing airway inflammation, while tiotropium was more effective in reducing airway remodeling. These findings underscore the importance of tailoring treatment approaches to address the specific needs of individual patients.
A Personalized Journey: Tailoring Asthma Treatment
This study highlights the importance of considering the unique characteristics of asthma in each patient when choosing treatment options. It's like understanding the specific challenges and terrain of a desert before deciding on the best route for a caravan. By understanding the different ways that montelukast and tiotropium impact airway inflammation and remodeling, clinicians can make more informed decisions about which add-on therapy is most appropriate for each patient.
Dr. Camel's Conclusion
This study, like a wise camel guide leading a caravan through a vast and challenging desert, offers insights into the diverse pathways to manage asthma. By recognizing the unique characteristics of each patient's condition and tailoring treatment approaches accordingly, clinicians can guide their patients toward a more comfortable and fulfilling journey.
Date :
- Date Completed 2020-04-30
- Date Revised 2021-12-04
Further Info :
Related Literature
English
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