Intrahepatic Administration of Liposomal Amphotericin B (Ambisome) for the Management of a Liver Abscess from <i>Candida albicans</i> in a Preterm Infant.

Author: AuritiCinzia, BersaniIliana, GennariFabrizio, PiersigilliFiammetta, RonchettiMaria Paola

Paper Details 
Original Abstract of the Article :
Hepatic fungal abscesses are rare in the neonatal period and often constitute a severe complication of the catheterization of the umbilical vessels. Such life-threatening lesions are observed more frequently in preterm than in other newborn infants and the optimal treatment remains uncertain. We pre...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256806/

データ提供:米国国立医学図書館(NLM)

A Rare Case: Treating a Liver Abscess in a Preterm Infant with Liposomal Amphotericin B

Imagine a fragile desert ecosystem where even a minor disruption can have significant consequences. Liver abscesses in preterm infants are like such disruptions, posing a serious threat to their delicate health. This research describes a case of a preterm neonate who developed a liver abscess due to a contaminated umbilical catheter, highlighting the challenges of treating this rare and severe condition.

The researchers report a successful treatment strategy involving surgical drainage of the abscess followed by direct intralesional administration of liposomal amphotericin B (Ambisome). This approach, never before described in neonates, proved to be safe and effective in resolving the abscess. It's like finding a specialized camel caravan equipped to navigate the unique challenges of a harsh desert environment.

Innovative Treatment Strategies for Neonatal Infections

This case report highlights the importance of innovative and tailored treatment approaches for managing complex infections in preterm infants. The use of liposomal amphotericin B directly into the abscess demonstrates a shift towards targeted and minimally invasive therapies, akin to employing precise tools to address the specific needs of a delicate desert ecosystem.

Hope for Preterm Infants with Liver Abscesses

This study offers hope for preterm infants with liver abscesses, demonstrating the potential of novel and effective treatment approaches. It's a reminder that even in the most challenging situations, medical innovation can provide solutions and improve patient outcomes. It's like discovering a hidden well of knowledge in the desert, offering life-giving resources to those in need.

Dr. Camel's Conclusion

This case report emphasizes the importance of individualized care and innovative treatment strategies in managing complex infections in preterm infants. It's a reminder that the desert of medicine is constantly evolving, with new discoveries and approaches offering hope for the most vulnerable patients.

Date :
  1. Date Completed 2019-10-23
  2. Date Revised 2019-10-23
Further Info :

Pubmed ID

30224526

DOI: Digital Object Identifier

PMC6256806

Related Literature

SNS
PICO Info
in preparation
Languages

English

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